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Table 1 Inhibition parameters (μg/ml) of the MeOH extract and compounds fromO. spinosaagainst microbial species

From: Antimicrobial and antioxidant flavonoids from the leaves of Oncoba spinosa Forssk. (Salicaceae)

Microorganisms

Inhibition parameters

MeOH extract

2

3

4

5

Reference drugs*

Enterobacter aerogenes ATCC13048

MIC

256

64

128

32

32

64

MBC

512

64

128

64

32

64

MBC/MIC

2

1

1

2

1

1

Escherichia coli ATCC8739

MIC

512

128

>256

128

64

64

MBC

1024

256

nd

128

64

64

MBC/MIC

2

2

nd

1

1

1

Klebsiella pneumoniae ATCC11296

MIC

256

64

256

32

8

16

MBC

512

64

256

64

16

16

MBC/MIC

2

1

1

2

2

1

Staphylococcus aureus

MIC

1024

256

>256

128

64

64

MBC

1024

>256

nd

128

128

64

MBC/MIC

1

nd

nd

1

2

1

Candida parapsilosis

MIC

1024

64

64

128

>256

256

MFC

>2048

64

128

256

nd

256

MFC/MIC

nd

1

2

2

nd

1

Candida albicans ATCC 9002

MIC

2048

128

>256

256

>256

128

MFC

>2048

128

nd

256

nd

128

MFC/MIC

nd

1

nd

1

nd

1

Cryptococcus neoformans IP 90526

MIC

1024

64

128

128

>256

128

MFC

>2048

64

128

128

nd

256

MFC/MIC

nd

1

1

1

nd

2

  1. *: nystatin for fungi and chloramphenicol for bacteria; nd: not determined; MIC: Minimum Inhibitory Concentration; MBC: Minimum Bactericidal Concentration; MFC: Minimum Fungicidal Concentration.