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Table 5 Effect of AHM and its fraction in hot plate test

From: Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis

Group

Dose/route

Latency time in seconds

  

0 min

30 min

60 min

120 min

Saline

10 ml, i.p.

9.83 ± 0.601

9.36 ± 0.317

9.3. ± 0.881

9.167 ± 0.44

AHM

50 mg/kg, p.o.

9.61 ± 0.1675

12.33 ± 0.881**

17.00 ± 0.577***

18.33 ± 0.66***

100 mg/kg, p.o.

9.76 ± 0.145

17.0 ± 0.57***

22.334 ± 1.201***

24.0 ± 0.557***

150 mg/kg, p.o.

9.74 ± 0.52

20.66 ± 0.881***

26.0 ± 0.577***

26.33 ± 0.334***

AHE

50 mg/kg, p.o.

9.63 ± 0.185

13.0 ± 0.577***

17.33 ± 0.667***

19.33 ± 0.333***

100 mg/kg, p.o.

9.83 ± 0.167

17.66 ± 0.88***

23.0 ± 0.577***

24.33 ± 0.333***

150 mg/kg, p.o.

9.667 ± 0.166

22.0 ± 0.577***

26.66 ± 0.33***

27.0 ± 0.577***

Diclofenac sodium

10 mg/kg, i.p.

9.67 ± 0.667

21.66 ± 0.88***

26.16 ± 0.89***

26.66 ± 1.00***

Fluoxetine

10 mg/kg, i.p.

9.66 ± 0.881

15.33 ± 0.334***

20.33 ± 0.90***

21.33 ± 0.667***

  1. Data values shown represent mean ± SEM (n = 6). **p < 0.01, ***p < 0.001 versus saline treated group (Two-way ANOVA followed by Bonferroni multiple comparison test).