Table 2 Effect of AHM and its fraction on carrageenan-induced paw edema in rats

Saline

2 ml, i.p.

1.2 ± 0.0265

2.66 ± 0.015

2.5 ± 0.095

2.24 ± 0.104

1.93 ± 0.053

AHM

50 mg/kg, p.o.

1.043 ± 0.03

2.488 ± 0.045

1.82 ± 0.062

1.56 ± 0.047

1.39 ± 0.032

(1.34 ± 0.917)

(40.23 ± 0.413)

(52.29 ± 3.12)

(52.46 ± 2.419)

100 mg/kg, p.o.

0.89 ± 0.04

2.311 ± 0.03

1.543 ± 0.02

1.301 ± 0.015

1.156 ± 0.05

(3.11 ± 1.6)

(49.41 ± 2.023)

(60.47 ± 0.429*)

(63.47 ± 0.457*)

150 mg/kg, p.o.

1.01 ± 0.037

2.423 ± 0.043

1.49 ± 0.07

1.27 ± 0.060

1.119 ± 0.06

(3.63 ± 1.135)

(63.07 ± 0.09*)

(75 ± 0.23**)

(85.06 ± 1.47**)

AHE

50 mg/kg, p.o.

1.05 ± 0.05

2.473 ± 0.013

1.797 ± 0.039

1.473 ± 0.046

1.343 ± 0.029

(2.295 ± 0.10)

(46.64 ± 0.63***)

(69.56 ± 0.564***)

(78.29 ± 1.000***)

100 mg/kg, p.o.

1.01 ± 0.29

2.307 ± 0.036

1.491 ± 0.010

1.274 ± 0.37

1.09 ± 0.51

(2.50 ± 0.20)

(67.14 ± 0.500***)

(81.159 ± 0.5***)

(92.07 ± 1.00***)

150 mg/kg, p.o.

1.01 ± 0.5

2.403 ± 0.05

1.46 ± 0.026

1.178 ± 0.019

1.036 ± 0.036

(3.86 ± 0.428)

(67.85 ± 1.00***)

(87.82 ± 1.00***)

(93.40 ± 1.00***)

Diclofenac sodium

10 mg/kg, i.p.

1.19 ± 0.015

2.576 ± 0.03

1.600 ± 0.02

1.426 ± 0.0305

1.27 ± 0.01

(5.52 ± 0.575)

(68.46 ± 0.815**)

(77.24 ± 0.192**)

(89.04 ± 2.048***)

Fluoxetine

10 mg/kg, i.p.

1.09 ± 0.064

2.50 ± 0.091

1.63 ± 0.04

1.343 ± 0.055

1.192 ± 0.017

(3.86 ± 0.212)

(58.461 ± 1.972*)

(75.64 ± 0.093**)

(85.98 ± 2.008**)

Aspirin

10 mg/kg, i.p.

1.157 ± 0.04

2.597 ± 0.032

1.736 ± 0.075

1.486 ± 0.066

1.34 ± 0.0264

(1.84 ± 0.50)

(55.46 ± 0.246*)

(68.30 ± 0.094**)

(74.93 ± 5.15**)