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Table 1 Histological grading of CCl 4 induced hepatic injury in male Wistar rats

From: Sesamol loaded solid lipid nanoparticles: a promising intervention for control of carbon tetrachloride induced hepatotoxicity

Group

Fatty changes

Inflammation

Fibrosis

NC

-

-

-

VC

-

-

-

S-SLNs PS

-

-

-

FS PS

-

-

-

Bla SLNs PS

-

-

-

CCl 4

++++

++++

++++

S-SLNs

+

++

++

FS

++

+++

+++

SILY

++

++

++

SR

+++

+++

++++

  1. -, normal occurrence; +, mild occurrence; ++, medium occurrence; +++, high occurrence; ++++, severe occurrence.