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Table 1 Histological grading of CCl 4 induced hepatic injury in male Wistar rats

From: Sesamol loaded solid lipid nanoparticles: a promising intervention for control of carbon tetrachloride induced hepatotoxicity

Group Fatty changes Inflammation Fibrosis
NC - - -
VC - - -
S-SLNs PS - - -
FS PS - - -
Bla SLNs PS - - -
CCl 4 ++++ ++++ ++++
S-SLNs + ++ ++
FS ++ +++ +++
SILY ++ ++ ++
SR +++ +++ ++++
  1. -, normal occurrence; +, mild occurrence; ++, medium occurrence; +++, high occurrence; ++++, severe occurrence.