Table 2 Baseline differences between high and low serum lignan CF patients on flaxseed diet
From: Flaxseed modulates inflammatory and oxidative stress biomarkers in cystic fibrosis: a pilot study
High lignans (n = 4) | Low lignans (n = 6) | p-value | |
|---|---|---|---|
Gender (male) | 2 (50%) | 1 (17%) | >0.1 |
Age (years) | 38.8 ± 13.8 | 27.3 ± 5.6 | 0.099 |
Sweat chloride (mM) | 74.3 ± 23.6 | 97.6 ± 12.0 | 0.070 |
DF508 homozygote (yes) | 0 (0%) | 3 (50%) | >0.1 |
Weight (lbs) | 161.0 ± 40.1 | 120.8 ± 18.9 | 0.062 |
BMI (Kg/M2) | 23.2 ± 3.9 | 21.2 ± 1.8 | >0.1 |
FEV1 (%predicted) | 82.8 ± 9.5 | 72.8 ± 20.2 | >0.1 |
Hemoglobin A1c | 5.5 ± 0.2 | 6.8 ± 1.1 | 0.051 |
CF related diabetes (yes) | 0 (0%) | 4 (66.7%) | 0.076 |
Pancreatic insufficiency (yes) | 2 (50%) | 6 (100%) | >0.1 |
Macrolide use (yes) | 0 (0%) | 6 (100%) | 0.005 |
Mucoid Pseudomonas (yes) | 2 (50%) | 3 (50%) | >0.1 |
Non-mucoid Pseudomonas (yes) | 2 (50%) | 5 (83.3%) | >0.1 |