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Table 2 Effect of herbal extracts and their different fractions on in vitro clot lysis

From: Effects of organic extracts and their different fractions of five Bangladeshi plants on in vitro thrombolysis

Herb/Drug

Extract/Fractions

% Clot lysis (mean ± S.D)

P-values (two-tailed) when compared to negative control (water)

Streptokinase (+ve control)

-

80.77 ± 1.12**

<0.001

Water (−ve control)

-

5.69 ± 3.09*

<0.05

Trema orientalis

Methanol (crude)

47.88 ± 6.12**

<0.001

Chloroform

46.44 ± 2.44**

<0.001

n-hexane

15.37 ± 0.29

 

Hydro-methanol

45.78 ± 3.32**

<0.001

Ethyl acetate

43.29 ± 2.98**

<0.001

Bacopa monnieri

Methanol (crude)

43.38 ± 8.69**

<0.001

Chloroform

48.39 ± 10.12 **

< 0.001

n-hexane

32.88 ± 10.72*

< 0.05

Hydro-methanol

30.73 ± 1.13*

< 0.05

Ethyl acetate

27.68 ± 1.34*

< 0.05

Capsicum frutiescens

Methanol (crude)

27.96 ± 0.50*

< 0.05

Chloroform

36.87 ± 1.27*

< 0.05

n-hexane

11.23 ± 1.29

 

Hydro-methanol

40.29 ± 1.26**

< 0.001

Ethyl acetate

19.82 ± 0.49

 

Brassica oleracea

Methanol (crude)

34.96 ± 4.60*

< 0.05

Chloroform

30.24 ± 0.95*

< 0.05

n-hexane

18.30 ± 3.55

 

Hydro-methanol

43.70 ± 1.97**

< 0.001

Ethyl acetate

15.29 ± 11.29

 

Urena sinuata

Methanol (crude)

39.30 ± 2.87*

< 0.05

Chloroform

47.89 ± 6.83**

< 0.001

n-hexane

26.58 ± 10.27*

< 0.05

Hydro-methanol

29.51 ± 3.62*

< 0.05

Ethyl acetate

38.29 ± 2.18*

< 0.05

  1. Values are mean ± SD, (n = 5); *P < 0.05, **P < 0.001, Dunnet test as compared to control (positive and negative). Statistical representation of the effective clot lysis percentage by herbal preparations, positive thrombolytic control (Streptokinase) and negative control (sterile distilled water) processed by paired t-test analysis (Dunnet test). Bold text indicates the highest clot lytic activity of chloroform extract of Bacopa monnieri.