Table 2 Effect of pantoprazole and lycopene on pH, volume of gastric juices total acidity, free acidity and esophagitis index in experimental animals
From: Effect of lycopene against gastroesophageal reflux disease in experimental animals
Group | Treatment | Intestinal pH | Volume of gastric juices (ml/100 g) | Total acidity (mEq/l) | Free acidity (mEq/l) | Esophagitis index |
|---|---|---|---|---|---|---|
Group-I | Sham control (Normal saline, 3 ml/kg,p.o) | 3.55 ± 0.31*** | 2.58 ± 0.38 (14.00) | 29.39 ± 0.97*** (18.95) | 20.99 ± 1.31*** (36.43) | 0.38 ± 0.35*** (87.46) |
Group-II | Esophagitis control (Normal saline, 3 ml/kg,p.o) | 2.73 ± 0.28 | 3.00 ± 0.45 | 36.26 ± 0.65 | 33.02 ± 0.98 | 3.03 ± 0.34 |
Group-III | Lycopene (50 mg/kg,p.o) | 3.65 ± 0.23*** | 1.57 ± 0.12 (47.66) | 30.056 ± 0.93*** (17.10) | 26.32 ± 1.14*** (20.29) | 1.33 ± 0.12*** (56.10) |
Group-IV | Lycopene (100 mg/kg,p.o) | 4.00 ± 0.34*** | 1.87 ± 0.12 (37.66) | 28.26 ± 0.79***a (20.06) | 25.79 ± 1.09*** (21.89) | 1.17 ± 0.16*** (61.38) |
Group-V | Pantoprazole (30 mg/kg,p.o) | 3.92 ± 0.30*** | 1.35 ± 3.40 (55.00) | 26.99 ± 1.36*** (25.56) | 22.32 ± 1.14*** (32.40) | 0.77 ± 0.16*** (74.59) |