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Figure 1 | BMC Complementary and Alternative Medicine

Figure 1

From: Medicinal value of asiaticoside for Alzheimer’s disease as assessed using single-molecule-detection fluorescence correlation spectroscopy, laser-scanning microscopy, transmission electron microscopy, and in silico docking

Figure 1

Schema of fluorescence correlation spectroscopy (FCS) measurement. (A). Confocal volume of FCS measurement. A pinhole provides an axial confinement to results in a tiny (less than femtoliter) detection volume (confocal volume). The fluorescence from the confocal volume is detected and processed using a digital correlator. (B). Principle of autocorrelation analysis of FCS measurements. δF(t), the fluorescence intensity fluctuations; <F(t)>, time average (< >) fluorescence intensity; G(τ), the auto-correlation curve is constructed from δF(t). (C). Mechanism of asiaticoside-induced inhibition at early steps of Aβ1–42 fibrillation.

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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