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Table 3 Associations of FTO rs7193144 (T > C) with determination of So-Eum or Tae-Eum type, after adjusting age, sex, and BMI

From: The obesity-risk variant of FTO is inversely related with the So-Eum constitutional type: genome-wide association and replication analyses

Population

SE versus NSE

TE versus NTE

MAF (n)

  

MAF (n)

  

SE

NSE

OR (95% CI)

P

TE

NTE

OR (95% CI)

P

Stage 1

0.106 (1903)

0.140 (1903)

0.706 (0.514, 0.968)

0.00210

0.135 (1903)

0.114 (1903)

1.097 (0.856, 1.407)

0.466

Stage 2

0.122 (833)

0.146 (835)

0.706 (0.514, 0.967)

0.0308

0.146 (837)

0.119 (831)

1.248 (0.885, 1.762)

0.207

Combined

0.111 (2736)

0.142 (2738)

0.693 (0.572, 0.839)

1.73E-04

0.138 (2740)

0.116 (2734)

1.146 (0.937, 1.402)

0.183

  1. Abbreviations: FTO fat mass and obesity–associated, BMI body mass index,SE So-Eum, NSE non-So-Eum, TE Tae-Eum, NTE non-Tae-Eum, MAF minor allele frequency, OR odds ratio, 95% CI, 95% confidence interval.
  2. Logistic regression analysis with adjustment for age, sex, and BMI in an additive genetic model: (stage 1) genome-wide association analysis in the KoGES population; (stage 2) replication analysis in the KCMS population.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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