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Table 3 Grade evidence profile of auricular acupuncture vs medications comparison

From: Auricular acupuncture with seed or pellet attachments for primary insomnia: a systematic review and meta-analysis

No. of studies

Design

Quality assessment

No. of patients

  

Effect

Quality

Importance

Risk of bias

Inconsistency

Indirectness

Imprecision

Other

Treatment

Control

Relative (95% CI)

Absolute

  

Effective Rate (Measured with: CCDM-3,PSQI et al.)

8

RCT

very serious1

no serious inconsistency

no serious indirectness

no serious imprecision

none4

268/293 (91.5%)

208/282 (73.8%)

RR 1.24 (1.15 ~ 1.35)

177/1000 (111 ~ 258)

LOW

CRITICAL

61.29%

147/1000 (92 ~ 215)

85.71%

206/1000 (129 ~ 300)

Sleep Efficiency % (Measured with: International Standard Sleep Efficiency; Better indicated by higher values)

1

RCT

serious1

serious2

no serious indirectness

serious 3

none4

36

36

—

MD 21.44 (16.30 ~ 26.58)

VERY LOW

IMPORTANT

Global Score On PAQI points (Measured with: PSQI; range of scores: 0-21; Better indicated by lower values)

1

RCT

serious1

serious2

no serious indirectness

serious 3

none4

32

31

—

MD -3.62 (-4.59 ~ -2.65)

VERY LOW

CRITICAL

Adverse Effect (Assessed with: SCL-90, TESS et al.)

4

RCT

very serious1

no serious inconsistency

no serious indirectness

no serious imprecision

none4

4/174 (2.3%)

45/164 (27.4%)

RR 0.11 (0.04 ~ 0.26)

244/1000 (203 ~ 263)

LOW

IMPORTANT

8.62%

77/1000 (64 ~ 83)

62.50%

556/1000 (463 ~ 600)

  1. 1. Methodological quality of included studies was not high.
  2. 2. With only one study involved, there were no heterogeneity assessment results for evaluation.
  3. 3. The pooled (cumulative) sample size was lower than the optimal information size (OIS) and/or the total enrollment was less than 400 (continuous data).
  4. 4. The number of included studies is not enough to estimate publication bias temporarily.
  5. Abbreviations:
  6. 95% CI: 95% Confidence Interval.
  7. CCMD-3: Chinese Classification of Mental Disorders, 3rd version.
  8. MD: Mean Difference.
  9. PSQI: Pittsburgh Sleep Quality Index.
  10. SCL-90: Symptom Check List-90.
  11. TESS: Treatment Emergent Symptom Scale.
  12. RR: Risk Radio.