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Table 1 Characteristics of Included studies

From: Auricular acupuncture with seed or pellet attachments for primary insomnia: a systematic review and meta-analysis

Study

Sample Size*

Randomized Method

Treatment

Control

Course

Outcome Measurements

Follow-Up

Safety

Assessment

(Male/Female)

of Bias**

Chen 2012 [46]

16/20

14/22

NR

SV

Diazepam

30 Days

Effective rate

NR

NR

?,?,-,?,+,?,?

Chyi Lo 2013 [58]

0/14

0/13

Random Number Table

MP

Sham AA

>21 Days

PSG, PSQI

NR

NR

+,?,+,-,+,+,-

Hisghman 2006 [60]

1/10

1/9

Computer Software

MP

Stainless Steel Pellet

17 Days

PSQI Sleep Diary, ISI, MOS SF-12, TEQ

12 Days

NR

+,+,+,?,+,+,-

Hu 2010 [47]

22/10

18/13

NR

SV

Diazepam

28 Days

Effective rate, PQSI, AIS

NR

NR

+,-,-,-,+,-,-

Jiang 2010 [48]

14/49

10/52

Random Number Table

SV

Sham AA

20-25 Days

PSQI

NR

NR

+,-,+,-,+,+,-

Jin 2012 [49]

13/27

15/25

NR

MP

Estazolam

7-14 Days

Effective rate, TESS

NR

Reported

+,-,-,?,?,?,?

Lin 2007 [59]

16/14

17/13

NR

SV

Sham AA

51 Days

Effective rate, EEG, PQSI

NR

NR

?,?,+,?,+,-,-

Liu 2008 [50]

26/74

37/63

Computer Software

MP

Sham AA

30 Days

PSQI

NR

NR

+,?,+,?,-,-,-

Luo 2010 [51]

11/10

9/12

NR

SV

Estazolam

30 Days

Effective rate, PQSI

NR

NR

?,?,-,?,-,-, -

Pi 2012 [52]

71/79

75/75

Computer Software

SV

Sham AA

8 Weeks

PSQI

NR

NR

+,-,+,-,-,-,-

Suen 2002 [57]

10/110***

NR

MP/SV

Junci Medulla Attachment

21 Days

Sleep Diary, Actigraphy

0.5-1 Year

NR

?,?,+,+,+,-,-

Wang 1993 [53]

10/20

12/18

NR

SV

Diazepam

20 Days

Effective rate, SCL-90

NR

Reported

?,?,-,?,+,-,-

Wang 2002 [54]

17/13

14/16

NR

MP

Diazepam

3-10 Days

Effective rate

NR

NR

?,?,-,?,+,-,-

Wei 2010 [55]

22/14

21/15

NR

NR

Estazolam

28 Days

Effective rate, Sleep Efficiency

NR

Reported

?,?,-,?,?,?,-

Zhang 2008 [56]

10/58

8/50

Random Number Table

MP

Estazolam

18 Days

Effective rate

NR

Reported

?,?,-,?,?,?,-

  1. Abbreviations: NR Not Reported, SV Semen Vaccariae Attachment, MP Magnetic Pearls Attachment, AA Auricular Acupuncture,PGSPolysomnography, PSQI Pittsburgh Sleep Quality Index, MOS SF-12 Medical Outcomes Study Short Form-12, TEQTreatment Expectancy Questionnaire, AIS Athens Insomnia Scale, TESS Treatment Emergent Symptom Scale, EEG electroencephalogram, SCL-90 Symptom CheckList-90. *Sample Size: sample size of treatment groups are on the left column, control groups on the right. **Assessment of Bias: the seven domains were random sequence generation, allocation concealment, blinding personnel and participants, blinding assessor, incomplete data outcome, selective reporting, and other forms of bias from left to right. +: low risk, - : high risk, ?: *** In study Suen 2002, the male to female ratio was not reported after grouping.