Figure 5From: Neuroprotective effect of the hairy root extract of Angelica gigas NAKAI on transient focal cerebral ischemia in rats through the regulation of angiogenesisEffect of AG extract on the expression of Akt, PI3K and ICAM in the brain of MCAO-induced ischemic rats. After MCAO/reperfusion, the protein was isolated from brain tissues, and assayed for expression of phosphorylated- or whole forms of Akt (A), PI3K (B) and ICAM (C) by western blot. β-actin was used as a control. Relative folds of p-Akt and PI3K and ICAM were calculated by normalization to Akt and β-actin, respectively. Data in the histogram are expressed as means ± SD of three independent experiments (n = 3 per group). **P < 0.01, and ***P < 0.001 vs. sham; and #P < 0.05, ##P < 0.01, and ###P < 0.001 vs. vehicle.Back to article page