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Table 4 Hematological parameters of rats in sub-acute toxicity of the methylene chloride/methanol extract of S. barteri

From: Toxicological studies of stem bark extract from Schefflera barteri Harms (Araliaceae)

Sexes Parameters studied Control 100 mg/kg 200 mg/kg 400 mg/kg 800 mg/kg
  Total RBC (x 106/mm3) 3.90 ± 0.22a 3.84 ± 0.56a 3.80 ± 0.37a 3.78 ± 0.55a 3.73 ± 0.47a
  Total WBC (x 103/mm3) 1&1103/mm3) 226.00 ± 19.50a 222.00 ± 16.10a 218.00 ± 12.07a 214.00 ± 10.25a 194.00 ± 16.46b
  Hematocrit (%) 45.40 ± 5.63a 50.00 ± 2.73a 48.40 ± 1.81a 49.20 ± 3.96a 49.20 ± 3.56a
Male Eosinophils (%) 0.80 ± 0.44a 1.00 ± 0.00a 1.00 ± 0.00a 1.00 ± 0.00a 1.00 ± 0.44a
  Neutrophils (%) 26.60 ± 4.77a 27.00 ± 5.00a 27.20 ± 4.14a 27.00 ± 7.00a 27.60 ± 3.03a
  Basophils (%) 0.40 ± 0.54a 0.40 ± 0.54a 0.41 ± 0.44a 0.40 ± 0.44a 0.40 ± 0.30a
  Monocytes (%) 6.20 ± 1.30a 6.20 ± 1.30a 5.60 ± 0.55a 5.40 ± 0.07a 5.40 ± 0.19a
  Lymphocytes (%) 66.00 ± 5.00a 65.60 ± 2.96a 64.80 ± 4.55a 61.80 ± 8.13a 61.00 ± 2.34a
  Total RBC (x 106/mm3) 3.39 ± 0.42a 3.37 ± 0.24a 3.35 ± 0.50a 3.37 ± 0.36a 3.30 ± 0.40a
  Total WBC (x 103/mm3) 248.00 ± 13.82a 246.00 ± 20.74a 244.00 ± 11.40a 168.00 ± 8.34b 150.00 ± 20.00b
  Hematocrit (%) 46.40 ± 2.79a 48.60 ± 5.32a 48.00 ± 5.43a 49.40 ± 3.71a 49.80 ± 2.59a
Female Eosinophils (%) 1.40 ± 0.54a 1.20 ± 0.44a 1.20 ± 0.44a 1.200 ± 0.00a 1.17 ± 0.00a
  Neutrophils (%) 30.00 ± 5.33a 29.20 ± 2.50a 25.80 ± 1.10b 24.60 ± 2.61b 23.60 ± 3.03b
  Basophils (%) 1.60 ± 0.54a 1.20 ± 0.44bc 1.00 ± 0.70bc 0.80 ± 0.44c 0.60 ± 0.54d
  Monocytes (%) 6.20 ± 0.77a 5.20 ± 0.83ab 4.60 ± 1.51b 4.20 ± 1.30b 4.60 ± 1.51b
  Lymphocytes (%) 61.80 ± 5.40a 64.00 ± 1.58a 65.40 ± 3.58a 65.20 ± 2.58a 65.20 ± 2.64a
  1. Data are expressed as mean ± S.E.M. n = 5. Values for a given group in a line followed by same letter as superscript are not significantly different according to Waller Duncan’s multiple comparison test (P < 0.05).WBCs = white blood cells, RBCs = red blood cells.