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Table 3 Relative organ weights indices (g/100g) of rats in sub-acute toxicity of the methylene Chloride/methanol extract of S. barteri

From: Toxicological studies of stem bark extract from Schefflera barteri Harms (Araliaceae)

  Doses (mg/kg) Liver Spleen Kidneys Lungs Heart Testis/ovaries
Male Control 3.68 ± 0.25b 0.32 ± 0.06b 0.82 ± 0.04a 0.67 ± 0.03a 0.34 ± 0.03c 1.21 ± 0.06a
100 3.84 ± 0.27b 0.37 ± 0.03a 0.79 ± 0.04a 0.68 ± 0.07a 0.37 ± 0.04b 1.17 ± 0.07a
200 4.10 ± 0.65a 0.37 ± 0.03a 0.79 ± 0.08a 0.68 ± 0.03a 0.38 ± 0.02b 1.16 ± 0.03a
400 4.11 ± 0.39a 0.37 ± 0.05a 0.79 ± 0.04a 0.69 ± 0.13a 0.40 ± 0.05a 1.16 ± 0.07a
800 4.63 ± 1.35a 0.37 ± 0.06a 0.79 ± 0.26a 0.70 ± 0.17a 0.40 ± 0.06a 1.16 ± 0.35a
Female Control 4.19 ± 0.36a 0.28 ± 0.08c 0.89 ± 0.08a 0.69 ± 0.14a 0.34 ± 0.03c 0.07 ± 0.02a
100 4.20 ± 0.98a 0.28 ± 0.06c 0.89 ± 0.02a 0.68 ± 0.14a 0.37 ± 0.04b 0.07 ± 0.02a
200 4.32 ± 0.33a 0.31 ± 0.04b 0.90 ± 0.07a 0.68 ± 0.10a 0.40 ± 0.02a 0.07 ± 0.01a
400 4.30 ± 0.75a 0.31 ± 0.02b 0.90 ± 0.08a 0.69 ± 0.04a 0.41 ± 0.03a 0.06 ± 0.01a
800 4.31 ± 0.50a 0.34 ± 0.07a 0.91 ± 0.06a 0.69 ± 0.06a 0.42 ± 0.05a 0.06 ± 0.02a
  1. Data are expressed as mean ± S.E.M. n = 5. Values for a given group in a line followed by different letter as superscript are significantly different according to Waller Duncan’s multiple comparison test (P < 0.05).