Treatment (v.o.) | Dose (mg/kg) | Evacuation Index (EI) |
---|
12
%
Tween 80 solution
|
-
|
15.0 (10.0 - 23.0)
|
Loperamide
|
5
|
0.0 (0.9 - 2.0)***
|
TAF-Cs |
62.5
|
13.5 (6.0 - 16.0)
|
TAF-Cs |
125
|
6.0 (4.0 - 8.0)
|
TAF-Cs |
250
|
1.0 (0.0 - 5.0)**
|
TAF-Cs |
500
|
1.0 (0.0 - 2.0)**
|
- Data are presented as median (minimum value – maximum value). Kruskal-Wallis test followed by Dunn’s multiple comparison test (** p <0.05, *** p <0.001 compared to the 12% Tween solution group). The TAF-Cs reduced evacuation index (250 and 500 mg/kg) compared to control group (12% Tween 80 solution).