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Table 1 Effect of oral administration of EtOHE-Cs, and loperamide on castor oil induced diarrhea in mice

From: Cissampelos sympodialis Eichl. (Menispermaceae), a medicinal plant, presents antimotility and antidiarrheal activity in vivo

Treatment (v.o.)

Dose (mg/kg)

Evacuation Index

(EI)

12 % Tween 80 solution

-

13.0 (12.0 - 18.0)

Loperamide

5

0.0 (0.0 - 1.0)**

EtOHE-Cs

62.5

12.0 (7.0 - 14.0)

EtOHE-Cs

125

13 (9.0 - 19.0)

EtOHE-Cs

250

11.5 (8.0 - 17.0)

EtOHE-Cs

500

4.0 (2.0 - 5.0)*

  1. Data are presented as median (minimum value – maximum value). Kruskal-Wallis test followed by Dunn’s multiple comparison test (* p <0.05, ** p <0.005 compared to the 12% Tween solution group). The EtOHE-Cs reduced evacuation index (500 mg/kg) compared to control group (12% Tween 80 solution).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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