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Table 3 Comparison between alterations in biochemical parameters in intervention and control group

From: Can red yeast rice and olive extract improve lipid profile and cardiovascular risk in metabolic syndrome?: a double blind, placebo controlled randomized trial

  Intervention group Placebo group Difference intervention group (absolute value and %) Difference placebo group (absolute value and %) 95% CI of difference p-value
Baseline intervention Baseline intervention
LDL (SD) mg/dL 164.3 (32.2) 122.6 (19.8) 170.7 (40.9) 171.5 (41.8) −41.7 (−23.7%) (28.3) 0.8 (0.5%) (24.3) 25.9; 56.0 <0.001
total CHOL (SD) mg/dL 247.5 (38.1) 204.0 (26.0) 251.2 (39.2) 255.1 (50.0) −43.5 (−16.5%) (31.1) 4.0 (2.0%) (23.7) 31.6; 63.3 <0.001
HDL (SD) mg/dL 56.3 (14.3) 58.0 (13.8) 53.5 (13.9) 54.3 (14.0) 1.6 (3.5%) (4.3) 0.8 (2.4%) (7.7) −4.3; 2.7 0.64
TG (SD) mg/dL 134.5 (57.9) 117.5 (53.9) 132.7 (49.5) 150.3 (84.4) −16.1 (−8.7%) (37.4) 19.3 (15.9%) (64.6) 5.7; 65.1 0.02
apoA (SD) mg/dL 162.2 (39.5) 171.2 (5.8) 157.3 (30.6) 161.1 (31.0) 4.7 (2.9%) (9.4) 3.9 (3.1%) (18.8) −18.5; 8.2 0.44
apoB (SD) mg/dL 115.5 (25.1) 96.6 (16.5) 119.3 (22.1) 126.3 (5.4) −19.0 (−14.7%) (18.3) 7.0 (6.0%) (14.1) 16.6; 35.5 <0.001
HbA1c (SD) mmol/mol 35.3 (3.2) 36.1 (2.6) 35.9 (6.4) 36.7 (6.5) 0.9 (2.9%) (1.6) 0.7 (2.0%) (1.6) −0.7; 1.1 0.61
oxLDL (SD) U/L 80.8 (34.5) 61.5 (21.4) 69.1 (17.7) 72.8 (22.2) −19.4 (−20.4%) (21.7) 3.7 (5.2%) (11.3) −35.2; −15.8 <0.001
  1. Values in italics are statistically significant.