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Table 3 Haematological parameters of male rats administered with Derris reticulata extract for 42 days

From: Antioxidant, α-glucosidase inhibitory activity and sub-chronic toxicity of Derris reticulata extract: its antidiabetic potential

Parameters Control Treatment
250 mg/kg 500 mg/kg 1000 mg/kg 2000 mg/kg
Male      
RBC (×106/μl) 9.15 ± 0.21 9.55 ± 0.11 8.56 ± 0.24 8.82 ± 0.28 8.80 ± 0.16
HGB (g/dl) 17.75 ± 0.25 17.50 ± 0.29 16.50 ± 0.50 17.25 ± 0.63 16.75 ± 0.25
HCT (%) 52.50 ± 1.56 50.25 ± 0.63 47.00 ± 1.68 48.00 ± 2.12 47.00 ± 0.91
WBC (×103/μl) 1.48 ± 0.28 5.58 ± 1.84 4.50 ± 1.43 3.80 ± 0.38 2.15 ± 0.70
LYM (%) 83.50 ± 2.96 75.50 ± 5.72 85.00 ± 2.48 85.50 ± 1.66 82.50 ± 5.12
MON (%) 3.25 ± 2.02 3.25 ± 1.11 2.75 ± 1.44 2.75 ± 0.85 2.00 ± 1.00
EOS (%) 0.25 ± 0.25 0.50 ± 0.29 0.75 ± 0.25 0.50 ± 0.29 0.75 ± 0.75
BAS (%) 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
PLT (103/μl) 731.3 ± 45.3 863.0 ± 44.5 638.8 ± 35.7 667.8 ± 21.4 798.8 ± 43.5
MCV (fl) 57.10 ± 0.58 52.63 ± 0.37* 54.90 ± 0.38* 54.30 ± 0.86* 53.45 ± 0.43*
MCH (pg) 19.25 ± 0.24 18.35 ± 0.10* 19.40 ± 0.14 19.18 ± 0.18 19.03 ± 0.11
MCHC (g/dl) 33.65 ± 0.30 34.88 ± 0.17* 35.38 ± 0.29* 35.28 ± 0.26* 35.63 ± 0.36*
  1. Values are expressed as mean ± S.E.M. (n = 4/group).
  2. *p < 0.05 statistically significant difference from control.
  3. Note that all of the parameters in treated groups that were different compared to control are within the normal ranges.