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Table 2 Haematological parameters of female rats administered with Derris reticulata extract for 42 days

From: Antioxidant, α-glucosidase inhibitory activity and sub-chronic toxicity of Derris reticulata extract: its antidiabetic potential

Parameters Control Treatment
250 mg/kg 500 mg/kg 1000 mg/kg 2000 mg/kg
Female      
RBC (×106/μl) 8.10 ± 0.17 7.94 ± 0.32 8.21 ± 0.19 8.12 ± 0.15 8.40 ± 0.16
HGB (g/dl) 16.00 ± 0.00 15.50 ± 0.65 16.25 ± 0.25 16.00 ± 0.00 16.75 ± 0.25
HCT (%) 45.50 ± 0.65 43.25 ± 2.10 44.00 ± 0.71 44.50 ± 0.87 45.00 ± 0.82
WBC (×103/μl) 1.33 ± 0.25 5.18 ± 2.26 1.08 ± 0.40 1.35 ± 0.35 1.58 ± 0.11
LYM (%) 86.25 ± 0.95 87.50 ± 3.40 76.25 ± 4.63 82.25 ± 4.84 88.50 ± 1.04
MON (%) 2.00 ± 0.41 3.50 ± 1.56 2.00 ± 0.71 1.75 ± 1.11 0.75 ± 0.48
EOS (%) 2.25 ± 0.85 1.00 ± 1.00 5.50 ± 4.27 3.50 ± 2.22 1.50 ± 0.29
BAS (%) 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
PLT (103/μl) 618.5 ± 43.1 811.8 ± 34.8* 807.3 ± 49.0* 818.8 ± 43.3* 752.8 ± 45.2*
MCV (fl) 56.00 ± 0.58 54.43 ± 0.80 53.78 ± 0.60 54.80 ± 0.46 53.63 ± 0.29
MCH (pg) 19.75 ± 0.40 19.68 ± 0.20 19.63 ± 0.34 19.78 ± 0.14 19.60 ± 0.06
MCHC (g/dl) 35.28 ± 0.55 36.10 ± 0.27 36.50 ± 0.27 36.08 ± 0.27 36.55 ± 0.25
  1. Values are expressed as mean ± S.E.M. (n = 4/group).
  2. *p < 0.05 statistically significant difference from control.
  3. Note that all of the parameters in treated groups that were different compared to control are within the normal ranges.