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Table 2 Haematological parameters of female rats administered with Derris reticulata extract for 42 days

From: Antioxidant, α-glucosidase inhibitory activity and sub-chronic toxicity of Derris reticulata extract: its antidiabetic potential

Parameters

Control

Treatment

250 mg/kg

500 mg/kg

1000 mg/kg

2000 mg/kg

Female

     

RBC (×106/μl)

8.10 ± 0.17

7.94 ± 0.32

8.21 ± 0.19

8.12 ± 0.15

8.40 ± 0.16

HGB (g/dl)

16.00 ± 0.00

15.50 ± 0.65

16.25 ± 0.25

16.00 ± 0.00

16.75 ± 0.25

HCT (%)

45.50 ± 0.65

43.25 ± 2.10

44.00 ± 0.71

44.50 ± 0.87

45.00 ± 0.82

WBC (×103/μl)

1.33 ± 0.25

5.18 ± 2.26

1.08 ± 0.40

1.35 ± 0.35

1.58 ± 0.11

LYM (%)

86.25 ± 0.95

87.50 ± 3.40

76.25 ± 4.63

82.25 ± 4.84

88.50 ± 1.04

MON (%)

2.00 ± 0.41

3.50 ± 1.56

2.00 ± 0.71

1.75 ± 1.11

0.75 ± 0.48

EOS (%)

2.25 ± 0.85

1.00 ± 1.00

5.50 ± 4.27

3.50 ± 2.22

1.50 ± 0.29

BAS (%)

0.00 ± 0.00

0.00 ± 0.00

0.00 ± 0.00

0.00 ± 0.00

0.00 ± 0.00

PLT (103/μl)

618.5 ± 43.1

811.8 ± 34.8*

807.3 ± 49.0*

818.8 ± 43.3*

752.8 ± 45.2*

MCV (fl)

56.00 ± 0.58

54.43 ± 0.80

53.78 ± 0.60

54.80 ± 0.46

53.63 ± 0.29

MCH (pg)

19.75 ± 0.40

19.68 ± 0.20

19.63 ± 0.34

19.78 ± 0.14

19.60 ± 0.06

MCHC (g/dl)

35.28 ± 0.55

36.10 ± 0.27

36.50 ± 0.27

36.08 ± 0.27

36.55 ± 0.25

  1. Values are expressed as mean ± S.E.M. (n = 4/group).
  2. *p < 0.05 statistically significant difference from control.
  3. Note that all of the parameters in treated groups that were different compared to control are within the normal ranges.