Figure 9
DECPR induced changes in expression of mitochondrial-dependent proteins. (A) Quantitative PCR analysis of apoptosis-associated genes in HT-29 cells showed significant up-regulation of Bax and down-regulation of Bcl-2 and Bcl-xl at the mRNA level. The data represent the means ± SEM of three independent experiments. *P < 0.05 compared with the untreated group. (B) Western blot analysis confirmed up-regulation of Bax and down-regulation of Bcl-2 and Bcl-xl at the protein level.