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Table 3 Effect of Holothuria arenicola extract on the liver oxidative statues of BDL rats

From: Anti-fibrotic effect of Holothuria arenicola extract against bile duct ligation in rats

Parameters Time period Groups % of improvement
Sham BDL HaE
MDA (nmol/gm tissue) 7 8.15 ± 0.57bc 8.79 ± 0.14c 8.10 ± 0.13bc 8.47
14 8.13 ± 0.59 bc 9.32 ± 0.37c 7.38 ± 0.46ab 23.86
28 8.13 ± 0.57bc 15.04 ± 0.42d 6.77 ± 0.60a 101.72
GSH (mg/gm tissue) 7 7.79 ± 0.91b 6.65 ± 0.21ab 7.7 ± 0.68b 13.47
14 7.84 ± 0.87b 5.28 ± 0.22a 8.41 ± 0.62b 39.79
28 7.84 ± 0.89b 4.77 ± 0.62a 7.64 ± 0.39b 36.61
CAT (U/min) 7 2.10 ± 0.19c 0.60 ± 0.03b 2.75 ± 0.31ac 102
14 2.09 ± 0.26c 0.56 ± 0.03b 2.47 ± 0.52ac 92
28 2.08 ± 0.17c 0.16 ± 0.08b 1.66 ± 0.28ab 72
GST (nmol/min/gm tissue) 7 0.05 ± 0.003c 0.03 ± 0.002b 0.04 ± 0.003ac 20
14 0.04 ± 0.008cd 0.03 ± 0.002b 0.04 ± 0.005ac 25
28 0.05 ± 0.004c 0.02 ± 0.006a 0.05 ± 0.002bc 60
SOD (U/gm tissue) 7 64.68 ± 2.18d 52.61 ± 4.83bc 54.87 ± 4.14bcd 3.94
14 67.22 ± 1.94d 39.66 ± 2.56a 47.401 ± 3.23ab 11.52
28 60.43 ± 1.28cd 38.54 ± 3.15a 60.81 ± 1.33cde 36.85
  1. Data are means ± SEM of six rats in each group.
  2. Unshared letters between groups are the significance values at p < 0.05.