Skip to main content

Table 3 Effect of Holothuria arenicola extract on the liver oxidative statues of BDL rats

From: Anti-fibrotic effect of Holothuria arenicola extract against bile duct ligation in rats

Parameters

Time period

Groups

% of improvement

Sham

BDL

HaE

MDA (nmol/gm tissue)

7

8.15 ± 0.57bc

8.79 ± 0.14c

8.10 ± 0.13bc

8.47

14

8.13 ± 0.59 bc

9.32 ± 0.37c

7.38 ± 0.46ab

23.86

28

8.13 ± 0.57bc

15.04 ± 0.42d

6.77 ± 0.60a

101.72

GSH (mg/gm tissue)

7

7.79 ± 0.91b

6.65 ± 0.21ab

7.7 ± 0.68b

13.47

14

7.84 ± 0.87b

5.28 ± 0.22a

8.41 ± 0.62b

39.79

28

7.84 ± 0.89b

4.77 ± 0.62a

7.64 ± 0.39b

36.61

CAT (U/min)

7

2.10 ± 0.19c

0.60 ± 0.03b

2.75 ± 0.31ac

102

14

2.09 ± 0.26c

0.56 ± 0.03b

2.47 ± 0.52ac

92

28

2.08 ± 0.17c

0.16 ± 0.08b

1.66 ± 0.28ab

72

GST (nmol/min/gm tissue)

7

0.05 ± 0.003c

0.03 ± 0.002b

0.04 ± 0.003ac

20

14

0.04 ± 0.008cd

0.03 ± 0.002b

0.04 ± 0.005ac

25

28

0.05 ± 0.004c

0.02 ± 0.006a

0.05 ± 0.002bc

60

SOD (U/gm tissue)

7

64.68 ± 2.18d

52.61 ± 4.83bc

54.87 ± 4.14bcd

3.94

14

67.22 ± 1.94d

39.66 ± 2.56a

47.401 ± 3.23ab

11.52

28

60.43 ± 1.28cd

38.54 ± 3.15a

60.81 ± 1.33cde

36.85

  1. Data are means ± SEM of six rats in each group.
  2. Unshared letters between groups are the significance values at p < 0.05.