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Table 1 Effect of Holothuria arenicola extract on liver function enzymes and total protein level in serum of BDL rats

From: Anti-fibrotic effect of Holothuria arenicola extract against bile duct ligation in rats

Parameters

Time period

Groups

% of improvement

Sham

BDL

HaE

ASAT (IU/L)

7

149.70 ± 9.57b

191.55 ± 5.87c

147.25 ± 7.82b

29.59

14

143.14 ± 9.08b

208.25 ± 10.02c

145.35 ± 10.4b

43.94

28

144.90 ± 8.63b

262.85 ± 7.93d

150.02 ± 5.64b

77.86

ALAT (IU/L)

7

55.51 ± 0.99a

77.31 ± 5.39b

71.65 ± 4.27b

10.20

14

54.18 ± 1.2a

103.86 ± 2.62c

67.95 ± 2.75b

66.27

28

55.52 ± 1.1a

110.35 ± 5.25c

71.05 ± 5.45b

70.15

Serum total protein (mg/100 ml)

7

4.11 ± 0.46a

12.62 ± 0.5c

10.5 ± 1.47b

51.58

14

4.15 ± 0.5a

14.86 ± 2.91b

12.95 ± 1.54bc

41.68

28

4.17 ± 0.51a

15.42 ± 1.89bc

13.43 ± 0.84bc

47.72

Serum albumin content (g/100 ml)

7

5.51 ± 0.32c

2.81 ± 0.15a

3.51 ± 0.52ab

14.42

14

5.86 ± 0.33c

3.84 ± 0.39ab

4.50 ± 0.22b

11.43

28

6.1 ± 0.22c

2.63 ± 0.47a

6.30 ± 0.08c

60.16

  1. Data are means ± SEM of six rats in each group.
  2. Unshared letters between groups are the significance values at p < 0.05.