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Table 1 Anti-proliferative activity (IC 50 values) of the methanol extract and fractions of Argemone gracilenta on selected cancer cell lines

From: In vitro anti-proliferative activity of Argemone gracilenta and identification of some active components

Cancer cell line IC50(μg/mL)
Methanol Hexane Ethyl acetate Ethanol Residual
M12.C3F6 46.20 ± 8.41ª 20.40 ± 2.30c 32.60 ± 1.10b 21.08 ± 0.84c 40.60 ± 10.08a
RAW 264.7 64.45 ± 8.97ª 36.06 ± 6.55d 41.27 ± 4.27c 55.18 ± 8.80b 64.65 ± 5.36ª
HeLa 78.87 ± 8.52b 70.62 ± 5.80c 126.28 ± 5.73ª > 200* > 200*
L-929 160.60 ± 2.15b 131.30 ± 3.39c 180.61 ± 4.37ª > 200* > 200*
  1. Data are shown as the mean ± SD from three independent repeats after a 48-h exposure to the test extract and fractions. Significant differences (p < 0.05) are indicated by different letters (a-d). The asterisk (*) represents the maximum concentration tested that did not reach IC50 values.