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Table 2 Determination of candidate proteins as potential biomarkers for Abnormal Savda on whole blood (plasma) by ELISA

From: Identification of plasma protein markers common to patients with malignant tumour and Abnormal Savda in Uighur medicine: a prospective clinical study

  Plasma protein level (ng/mL) ANOVA test (pvalue)
ASt (n = 71) nASt (n = 65) NC (n = 40) FP ASt/nASt ASt/NC nASt/NC
SAA1 12.755 ± 6.990 9.468 ± 6.965 6.790 ± 4.529 5.645 .035 .002 .150
     .005    
PIGR 37.868 ± 14.336 45.298 ± 14.325 60.734 ± 11.913 13.249 .038 .000 .001
     .000    
ORM1 19.400 ± 5.557 22.217 ± 5.279 20.234 ± 2.940 2.309 .037 .589 .206
     .106    
ZNF452 0.758 ± 0.362 0.701 ± 0.538 1.698 ± 1.112 16.84 .724 .004 .003
     .000    
SPP24 2270.987 ± 304.153 2090.084 ± 264.598 1792.224 ± 266.44 15.057 .018 .000 .001
     .000    
FASN 0.847 ± 0.275 1.129 ± 0.654 2.501 ± 1.114 34.913 .015 .000 .000
     .000    
LBP 204.220 ± 24.523 199.499 ± 46.947 11.609 ± 4.454 146.833 .624 .000 .000
     .000    
HYAL1 12.666 ± 5.069 11.785 ± 5.225 11.351 ± 5.330 4.71 .486 .368 .769
     .626    
THBS1 4.154 ± 2.641 3.366 ± 1.922 1.579 ± 1.100 7.777 .148 .000 .008
     .001    
  1. ASt, nASt or NC, refer to patients with Abnormal Savda type tumours, non-Abnormal Savda type tumours, or normal controls, respectively; ASt/nASt, ASt/NC, nASt/NC, comparative analysis between two groups indicated, with statistical significance at p< 0.05.