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Table 2 Determination of candidate proteins as potential biomarkers for Abnormal Savda on whole blood (plasma) by ELISA

From: Identification of plasma protein markers common to patients with malignant tumour and Abnormal Savda in Uighur medicine: a prospective clinical study

 

Plasma protein level (ng/mL)

ANOVA test (pvalue)

ASt (n = 71)

nASt (n = 65)

NC (n = 40)

FP

ASt/nASt

ASt/NC

nASt/NC

SAA1

12.755 ± 6.990

9.468 ± 6.965

6.790 ± 4.529

5.645

.035

.002

.150

    

.005

   

PIGR

37.868 ± 14.336

45.298 ± 14.325

60.734 ± 11.913

13.249

.038

.000

.001

    

.000

   

ORM1

19.400 ± 5.557

22.217 ± 5.279

20.234 ± 2.940

2.309

.037

.589

.206

    

.106

   

ZNF452

0.758 ± 0.362

0.701 ± 0.538

1.698 ± 1.112

16.84

.724

.004

.003

    

.000

   

SPP24

2270.987 ± 304.153

2090.084 ± 264.598

1792.224 ± 266.44

15.057

.018

.000

.001

    

.000

   

FASN

0.847 ± 0.275

1.129 ± 0.654

2.501 ± 1.114

34.913

.015

.000

.000

    

.000

   

LBP

204.220 ± 24.523

199.499 ± 46.947

11.609 ± 4.454

146.833

.624

.000

.000

    

.000

   

HYAL1

12.666 ± 5.069

11.785 ± 5.225

11.351 ± 5.330

4.71

.486

.368

.769

    

.626

   

THBS1

4.154 ± 2.641

3.366 ± 1.922

1.579 ± 1.100

7.777

.148

.000

.008

    

.001

   
  1. ASt, nASt or NC, refer to patients with Abnormal Savda type tumours, non-Abnormal Savda type tumours, or normal controls, respectively; ASt/nASt, ASt/NC, nASt/NC, comparative analysis between two groups indicated, with statistical significance at p< 0.05.