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Table 3 IC 50 values (μg/ml) of Australian Aboriginal extracts on two cancer cell lines and the non-cancerous MDCK and 3T3-L1 cell lines

From: Exploring the anti-diabetic potential of Australian Aboriginal and Indian Ayurvedic plant extracts using cell-based assays

Australian Aboriginal plant extracts/Control

 

Cell lines

 

3T3-L1 pre adipocytes

MDCK

A549

HeLa

Vincristine

Not determined

145.83 ± 5.20

0.6 ± 0.02

0.039 ± 0.01

AK

202.36 ± 21.44

550.03 ± 36.20

75.17 ± 6.25

13.73 ± 1.51*

AL

240.70 ± 65.22

398.51 ± 31.26

298.6 ± 44.45

110.61 ± 35.82

AT

306.46 ± 65.56

567.38 ± 52.59

210.85 ± 30.82

27.00 ± 14.28*

BL

386.95 ± 56.32

331.33 ± 30.90

84.08 ± 24.37

229.11 ± 40.57

ED

256.34 ± 59.53

460.25 ± 20.96

91.26 ± 19.84

142.50 ± 29.27

SL

173.14 ± 24.86

406 ± 24.31

162.95 ± 27.34

186.66 ± 62.21

SS

158.81 ± 25.53

283.66 ± 12.64

112.28 ± 13.28

110.11 ± 11.91

  1. Data are expressed as mean ± SEM of independent experiment (n = 3). *denotes IC50 less than 30 μg/ml which is considered as an active extract against cancer cells.