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Table 1 Functional groups of frankincense oil-regulated genes in bladder cancer J82 cells

From: Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity

Function

Gene Symbol

Description

Cytokines

 

CCL2

chemokine (C-C motif) ligand 2

 

CCL5

chemokine (C-C motif) ligand 5

 

CMTM8

CKLF-like MARVEL transmembrane domain containing 8

 

CXCL2

chemokine (C-X-C motif) ligand 2

 

IL1A

interleukin 1, alpha

 

IL6

interleukin 6 (interferon, beta 2)

 

IL8

interleukin 8

Enzymes – kinases

 

ABL2

v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

 

AXL

AXL receptor tyrosine kinase

 

CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

 

CLK1

CDC-like kinase 1

 

DLG1

discs, large homolog 1 (Drosophila)

 

FGFR1

fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)

 

PSTK

phosphoseryl-tRNA kinase

 

SGK1

serum/glucocorticoid regulated kinase 1

 

SNF1LK

SNF1-like kinase

 

TAOK1

TAO kinase 1

 

TRIB1

tribbles homolog 1 (Drosophila)

Enzymes – peptidases

 

RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

Enzymes – phosphatases

 

DUSP10

dual specificity phosphatase 10

 

DUSP2

dual specificity phosphatase 2

 

DUSP5

dual specificity phosphatase 5

 

MTMR6

myotubularin related protein 6

 

NUDT2

nudix (nucleoside diphosphate linked moiety X)-type motif 2

 

PPP3R1

protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform

 

PTPN23

protein tyrosine phosphatase, non-receptor type 23

Membrane Receptors

 

PLAUR

plasminogen activator, urokinase receptor

 

PLXNA1

plexin A1

 

PLXNA3

plexin A3

 

SSTR1

somatostatin receptor 1