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Table 5 Effects of treatment with Tridax procumbens extract on oral glucose tolerance (OGTT) after 30 days of drug administration in normal and alloxan diabetic rats.

From: Evaluation of hypoglycemic and anti-hyperglycemic potential of Tridax procumbens (Linn.)

Group

(n = 6)

Dose

(mg/kg b wt)

Blood Glucose levels (mg/dl)

  

-30 min

0 min

30 min

60 min

90 min

120 min

Normal Control

-

79.12 ± 2.8a

80.16 ± 3.6a

146.5 ± 9.6b

152.4 ± 8.4b

121.6 ± 21.6c

102.3 ± 32.0d

Normal+ Extract

250

78.54 ± 4.1a

76.60 ± 3.0a

151.0 ± 11.7b

143.6 ± 9.6b

119.2 ± 16.3c

87.5 ± 12.3d

Normal+ Extract

500

79.58 ± 3.2a

73.60 ± 5.8a

149.4 ± 8.2b

136.6 ± 11.0c

120.6 ± 11.6c

84.6 ± 19.0d

Diabetic Control

-

508.2 ± 4.7a

512.40 ± 9.6a

HIb

597.2 ± 3.4b

580.6 ± 32.0b

547.5 ± 9.2c

Diabetic+ Extract

250

186.6 ± 2.4a

181.24 ± 12.5a

299.8 ± 43.0b

261.0 ± 34.2c

196.4 ± 14.9d

169.6 ± 14.4e

Diabetic+ Extract

500

163.0 ± 6.8a

165.00 ± 10.2a

302.4 ± 19.6b

271.0 ± 18.3c

190.4 ± 28.4d

160.3 ± 18.4e

Diabetic+ Glibenc-lamide

10

190.4 ± 4.6a

190.00 ± 11.4a

285.6 ± 46.0b

256.6 ± 29.4c

231.0 ± 17.2c

199.6 ± 10.3d

  1. Values represent mean ± SEM (n = 6).
  2. *Values for a given group in a row followed by same letter as superscript are not significantly different according to Tukey's multiple comparison procedure (at P < 0.05).
  3. HI = High Blood Glucose Level i. e. above 600 mg/dl