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Table 3 Effects of treatment with Tridax procumbens extract on body weight in normal and alloxan diabetic rats.

From: Evaluation of hypoglycemic and anti-hyperglycemic potential of Tridax procumbens (Linn.)

Group

(n = 6)

Dose

(mg/kg b.wt)

BODY WEIGHT IN GRAMS

  

Alloxanα) dosing

DAYS AFTER DOSING

   

0 dβ)

7 d

15 d

21 d

30 dγ)

Normal Control

-

162.6 ± 4.2a

201.3 ± 1.9 b (23.80)

208.4 ± 2.1b (3.52)

217.4 ± 6.2b (4.31)

225.8 ± 4.9c (3.86)

234.4 ± 7.8 c (3.80)

Normal+ Extract

250

160.0 ± 3.6a

196.2 ± 2.7 b (22.62)

205.5 ± 1.9 b (4.74)

213.2 ± 5.4 c (3.74)

221.1 ± 3.2 c (3.70)

228.6 ± 4.2 c (3.39)

Normal+ Extract

500

156.1 ± 2.4a

197.6 ± 2.1 b (26.58)

205.1 ± 3.0 b (3.79)

210.4 ± 4.3 b (2.58)

218.3 ± 3.7b (3.75)

227.3 ± 2.9c (4.12)

Diabetic Control

-

156.0 ± 2.9a

163.4 ± 2.8b (4.74)

160.4 ± 3.2b -(1.83)

155.4 ± 4.0 c -(3.11)

154.6 ± 5.2b -(0.51)

145.6 ± 5.2c -(5.82)

Diabetic+ Extract

250

157.0 ± 3.1a

164.2 ± 1.7b (4.58)

165.4 ± 1.9b (0.73)

167.7 ± 2.8b (1.39)

176.3 ± 3.2b (5.12)

182.6 ± 5.0c (3.57)

Diabetic+ Extract

500

162.9 ± 2.2a

171.2 ± 1.4b (5.09)

173.3 ± 2.1b (1.22)

176.5 ± 3.1b (1.84)

183.1 ± 2.5b (3.73)

189.2 ± 6.4c (3.33)

Diabetic+ Glibenc-lamide

10

157.3 ± 1.9a

165.3 ± 2.4b (5.08)

167.3 ± 3.0b (1.20)

168.2 ± 2.8b (0.53)

174.0 ± 8.7b (2.83)

176.7 ± 3.8b (1.55)

  1. Values represent mean ± SEM (n = 6).
  2. *Values for a given group in a row followed by same letter as superscript are not significantly different according to Tukey's multiple comparison procedure (at P < 0.05).
  3. α) At alloxan dosing; β) at initial dosing after fasting (15 d after alloxan dosing); γ) at sacrifice after fasting
  4. Values given in parenthesis are percent (%) body weight change compared to previous observation of their respective group