Table 3 The characteristics of subjects with and without overall satisfaction with the treatment.
Patients' characteristics | Overall satisfied | Statistics | |
|---|---|---|---|
Yes | No | ||
Number of subjects | 58 | 19 | |
Male (no) | 32 (55%) | 11 (58%) | ns (p = 1.00) |
Age in years (mean) | 49.6 (14.8) | 39.2 (10.6) | p = 0.002 |
BMI (mean) | 25.8 (2.6) | 26.3 (3.8) | ns (p = 0.51) |
Cups of coffee per day (mean) | 3.0 (2.2) | 3.4 (3.0) | ns (p = 0.72) |
Smoking (daily/past/never) (no) | 13/17/28 | 6/11/2 | p = 0.029 |
Duration of reflux symptoms in years (mean) | 7.7 (7.7) | 9.0 (8.9) | ns (p = 0.55) |
Esophagitis (NERD/LAgrA/LAgrB) (no) | 10/28/20 | 2/9/8 | ns (p = 0.46) |
Hiatal hernia (no) | 21 (36%) | 6 (32%) | ns (p = 0.78) |
Symptom score at inclusion (mean) | 11.2 (3.6) | 11.9 (5.0) | ns (p = 0.49) |
Symptom score at the end of treatment (mean) | 6.1 (3.4) | 9.5 (4.8) | p = 0.004 |
Weeks of satisfactory relief (mean proportion) | 94.6% (13.6) | 18.7% (32.0) | p < 0.001 |
Prefer same drug after the trial (no) | 48 (83%) | 1 (5%) | p < 0.001 |
Prefer regular treatment (no) | 7 (12%) | 5 (26%) | ns (p = 0.15) |
Rapid relapse of symptoms (no) | 15 (26%) | 11 (58%) | p = 0.023 |
Delayed onset of effect (no) | 9 (16%) | 5 (26%) | ns (p = 0.32) |
Too many tablets (no) | 6 (10%) | 7 (37%) | p = 0.013 |
Diarrhoea (no) | 6 (10%) | 1 (5%) | ns (p = 0.67) |