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Table 2 Median BP ± SE (SD)

From: Dark chocolate or tomato extract for prehypertension: a randomised controlled trial

Median SBP ± SE (SD)
   Phase 1 Phase 2
  N Parallel RCT, 3 groups Crossover of two active groups
Group wk 0 wk 4 wk 8 washout wk 12 P-value within group over time wk 0–12 Group wk 16 wk 20 Washout wk 24 P-value within group over time wk 0–24
Chocolate 11 135.0 ± 3.8 (12.5) 136.9 ± 4.3 (14.1) 133.1 ± 3.5 (11.7) 128.6 ± 4.5 (15.0) .23 Tomato 131.0 ± 4.1 (13.6) 131.2 ± 4.3 (14.2) 127.6 ± 3.9 (13.0) .57
Tomato 15 128.2 ± 3.0 (11.4) 130.9 ± 4.1 (15.8) 125.7 ± 2.7 (10.6) 129.3 ± 3.0 (11.8) .82 Chocolate 125.4 ± 2.9 (10.9) 126.8 ± 2.8 (10.3) 124.2 ± 2.2 (8.1) .79
Control 10 135.7 ± 3.9 (12.4) 134.3 ± 4.8 (15.2) 130.8 ± 5. 8 (18.3) 134.0 ± 3.9 (12.3) .98      
Median DBP ± SE (SD)
Chocolate 11 83.6 ± 3.2 (10.6) 83.9 ± 4. 0 (13.4) 84.5 ± 3. 5 (11.6) 80.8 ± 3. 8 (12.5) .49 Tomato 82.8 ± 2.8 (9.3) 82.6 ± 3. 4 (11.3) 79.7 ± 3.7 (12.3) .91
Tomato 15 79.1 ± 1. 9 (7.5) 79.0 ± 2.7 (10.4) 77.5 ± 1.9 (7.4) 79.2 ± 2.2 (8.6) .98 Chocolate 76.4 ± 2.1 (7.7) 77.9 ± 2.2 (8.2) 77.8 ± 1.7 (6.2) 1.0
Control 10 77.8 ± 2.7 (8.6) 76.6 ± 3.0 (9.4) 77.3 ± 3.2 (10.0) 77.3 ± 3.0 (9.4) .94      
  1. P-values were calculated using linear mixed model analysis. Between group differences over time (phases 1 and 2) were not significant (P-values not shown).