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Table 1 Comparative IC50 values of F4 fraction and vincristine over tumor cell lines and normal human cells.

From: Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells

CELLS A375 K562 Mel Rel PBMC no PHA PBMC with PHA Fibroblasts
F4 fraction (IC50 μg/ml) 35.2 ± 1.35* 32 ± 1.41 36.3 ± 1.64. 121 ± 2.6 * 151 ± 8.3 * 440 ± 15 *
Vincristine (IC50 nM) 132 ± 10* 61 ± 4* 124.5 ± 15* 247 ± 22* 197 ± 20* 85.5 ± 24*
  1. ± = SEM, p < 0.05
  2. The IC50 values of tumor cell lines and normal human cells treated with F4 fraction were calculated with Minitab 14 Statistical Software Probit analysis. The values are mean ± SEM from three independent experiments.