Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir

Table 3 Glucose Utilization (M) and Insulin Sensitivity (M/I) Measured by the Hyperinsulinemic Euglycemic Clamp in Healthy Volunteers at Baseline, After 3 Days of IDV, and After Co-Administration of IDV and AG (1 gram every 8 hours) for 14 Days

Subject	M (mg/kg FFM/min)			M/I (mg/kg FFM/min per μU/ml of insulin)
	Baseline	IDV Alone	IDV + AG	Baseline	IDV Alone	IDV + AG
4	8.25	5.69	5.79	0.121	0.072	0.072
5	8.46	8.20	10.35	0.135	0.138	0.193
6	4.58	3.93	4.01	0.055	0.049	0.059
7	11.52	7.14	7.82	0.173	0.141	0.134
8	8.88	9.02	7.29	0.132	0.155	0.118
9	4.10	2.74	-	0.062	0.037	-
10	10.14	9.54	9.94	0.119	0.126	0.123
11	9.60	8.62	5.93	0.157	0.115	0.107
12	6.19	4.24	3.51	0.078	0.062	0.042
13	8.62	7.82	7.66	0.137	0.123	0.113
14	4.60	2.62	2.37	0.068	0.038	0.030

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