Figure 11

Effects of Kihi-to on Aβ(25–35)-induced cell death in cortical neurons. After cultivation for 3 days, the cortical neurons were treated with or without (Cont) Aβ(25–35). The cells were simultaneously treated with Kihi-to (1 μg/ml), [Gly¹⁴]-Humanin (10 nM) or vehicle (Veh). Four days after the treatment, cell viability was measured (B). Photographs show representative images (A). Scale = 100 μm. *p < 0.05 vs. Cont, n = 4 (one-way ANOVA followed by Holm-Sidak post hoc test).