TY - JOUR AU - DeKosky, S. T. AU - Scheff, S. W. PY - 1990 DA - 1990// TI - Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity JO - Ann Neurol VL - 27 UR - https://doi.org/10.1002/ana.410270502 DO - 10.1002/ana.410270502 ID - DeKosky1990 ER - TY - JOUR AU - Dickson, T. C. AU - Vickers, J. C. PY - 2001 DA - 2001// TI - The morphological phenotype of β-amyloid plaques and associated neuritic changes in Alzheimer's disease JO - Neuroscience VL - 105 UR - https://doi.org/10.1016/S0306-4522(01)00169-5 DO - 10.1016/S0306-4522(01)00169-5 ID - Dickson2001 ER - TY - JOUR AU - Terry, R. D. AU - Masliah, E. AU - Salmon, D. P. AU - Butters, N. AU - DeTeresa, R. AU - Hill, R. AU - Hansen, L. A. AU - Katzman, R. PY - 1991 DA - 1991// TI - Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment JO - Ann Neurol VL - 30 UR - https://doi.org/10.1002/ana.410300410 DO - 10.1002/ana.410300410 ID - Terry1991 ER - TY - JOUR AU - Tohda, C. AU - Kuboyama, T. AU - Komatsu, K. PY - 2005 DA - 2005// TI - Search for natural products related to regeneration of the neuronal network JO - Neurosignals VL - 14 UR - https://doi.org/10.1159/000085384 DO - 10.1159/000085384 ID - Tohda2005 ER - TY - JOUR AU - Tohda, C. AU - Matsumoto, N. AU - Zou, K. AU - Meselhy, M. R. AU - Komatsu, K. PY - 2002 DA - 2002// TI - Axonal and dendritic extension by protopanaxadiol-type saponins from ginseng drugs in SK-N-SH cells JO - Jpn J Pharmacol VL - 90 UR - https://doi.org/10.1254/jjp.90.254 DO - 10.1254/jjp.90.254 ID - Tohda2002 ER - TY - JOUR AU - Tohda, C. AU - Matsumoto, N. AU - Zou, K. AU - Meselhy, M. R. AU - Komatsu, K. PY - 2004 DA - 2004// TI - Aβ(25–35)-induced memory impairment, axonal atrophy, and synaptic loss are ameliorated by M1, A metabolite of protopanaxadiol-type saponins JO - Neuropsychopharmacology VL - 29 UR - https://doi.org/10.1038/sj.npp.1300388 DO - 10.1038/sj.npp.1300388 ID - Tohda2004 ER - TY - JOUR AU - Tohda, C. AU - Tamura, T. AU - Matsuyama, S. AU - Komatsu, K. PY - 2006 DA - 2006// TI - Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus JO - Brit J Pharmacol VL - 149 UR - https://doi.org/10.1038/sj.bjp.0706865 DO - 10.1038/sj.bjp.0706865 ID - Tohda2006 ER - TY - JOUR AU - Naito, R. AU - Tohda, C. PY - 2006 DA - 2006// TI - Characterization of anti-neurodegenerative effects of Polygala tenuifolia in Aβ(25–35)-treated cortical neurons JO - Biol Pharm Bull VL - 29 UR - https://doi.org/10.1248/bpb.29.1892 DO - 10.1248/bpb.29.1892 ID - Naito2006 ER - TY - JOUR AU - Seltzer, B. PY - 2007 DA - 2007// TI - Donepezil: an update JO - Expert Opin Pharmacother VL - 8 UR - https://doi.org/10.1517/14656566.8.7.1011 DO - 10.1517/14656566.8.7.1011 ID - Seltzer2007 ER - TY - JOUR AU - Tohda, C. AU - Tamura, T. AU - Komatsu, K. PY - 2003 DA - 2003// TI - Repair of amyloid β(25–35)-induced memory impairment and synaptic loss by a Kampo formula, Zokumei-to JO - Brain Res VL - 990 UR - https://doi.org/10.1016/S0006-8993(03)03449-8 DO - 10.1016/S0006-8993(03)03449-8 ID - Tohda2003 ER - TY - JOUR AU - Gruden, M. A. AU - Davudova, T. B. AU - Malisauskas, M. AU - Zamotin, V. V. AU - Sewell, R. D. AU - Voskresenskaya, N. I. AU - Kostanyan, I. A. AU - Sherstnev, V. V. AU - Morozova-Roche, L. A. PY - 2004 DA - 2004// TI - Autoimmune responses to amyloid structures of Abeta(25–35) peptide and human lysozyme in the serum of patients with progressive Alzheimer's disease JO - Dement Geriatr Cogn Disord VL - 18 UR - https://doi.org/10.1159/000079197 DO - 10.1159/000079197 ID - Gruden2004 ER - TY - JOUR AU - Pike, C. J. AU - Walencewicz-Wasserman, A. J. AU - Kosmoski, J. AU - Cribbs, D. H. AU - Glabe, C. G. AU - Cotman, C. W. PY - 1995 DA - 1995// TI - Structure-activity analyses of β-amyloid peptides: contribution of the β25–35 region to aggregation and neurotoxicity JO - J Neurochem VL - 64 UR - https://doi.org/10.1046/j.1471-4159.1995.64010253.x DO - 10.1046/j.1471-4159.1995.64010253.x ID - Pike1995 ER - TY - JOUR AU - Yankner, B. A. AU - Duffy, L. K. AU - Kirschner, D. A. PY - 1990 DA - 1990// TI - Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides JO - Science VL - 250 UR - https://doi.org/10.1126/science.2218531 DO - 10.1126/science.2218531 ID - Yankner1990 ER - TY - JOUR AU - Grace, E. A. AU - Busciglio, J. PY - 2003 DA - 2003// TI - Aberrant activation of focal adhesion proteins mediates fibrillar amyloid β-induced neuronal dystrophy JO - J Neurosci VL - 23 ID - Grace2003 ER - TY - JOUR AU - Kuboyama, T. AU - Tohda, C. AU - Komatsu, K. PY - 2005 DA - 2005// TI - Neuritic regeneration and synaptic reconstruction induced by withanolide A JO - Brit J Pharmacol VL - 144 UR - https://doi.org/10.1038/sj.bjp.0706122 DO - 10.1038/sj.bjp.0706122 ID - Kuboyama2005 ER - TY - JOUR AU - Klementiev, B. AU - Novikova, T. AU - Novitskaya, V. AU - Walmod, P. S. AU - Dmytriyeva, O. AU - Pakkenberg, B. AU - Berezin, V. AU - Bock, E. PY - 2007 DA - 2007// TI - A neural cell adhesion molecule-derived peptide reduces neuropathological signs and cognitive impairment induced by Aβ25–35 JO - Neuroscience VL - 145 UR - https://doi.org/10.1016/j.neuroscience.2006.11.060 DO - 10.1016/j.neuroscience.2006.11.060 ID - Klementiev2007 ER - TY - JOUR AU - Azuma, K. AU - Yuhisa, H. AU - Moriguchi, A. AU - Rakuki, H. AU - Ogiwara, T. PY - 2004 DA - 2004// TI - (meeting report, title and abstract in Japanese) JO - Jpn J Geriatrics VL - 41 ID - Azuma2004 ER - TY - JOUR AU - Yabe, T. AU - Toriizuka, K. AU - Yamada, H. PY - 1995 DA - 1995// TI - Effect of Kampo medicine acetyltransferase activity in rat embryo septal cultures JO - J Trad Med VL - 12 ID - Yabe1995 ER - TY - JOUR AU - Hashimoto, Y. AU - Niikura, T. AU - Ito, Y. AU - Sudo, H. AU - Hata, M. AU - Arakawa, E. AU - Abe, Y. AU - Kita, Y. AU - Nishimoto, I. PY - 2001 DA - 2001// TI - Detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insults detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insults JO - J Neurosci VL - 21 ID - Hashimoto2001 ER - TY - JOUR AU - Schlaepfer, W. W. AU - Lee, C. AU - Lee, V. M. AU - Zimmerman, U. J. PY - 1985 DA - 1985// TI - An immunoblot study of neurofilament degradation in situ and during calcium-activated proteolysis JO - J Neurochem VL - 44 UR - https://doi.org/10.1111/j.1471-4159.1985.tb05442.x DO - 10.1111/j.1471-4159.1985.tb05442.x ID - Schlaepfer1985 ER - TY - JOUR AU - Billger, M. AU - Wallin, M. AU - Karlsson, J. O. PY - 1988 DA - 1988// TI - Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules JO - Cell Calcium VL - 9 UR - https://doi.org/10.1016/0143-4160(88)90036-X DO - 10.1016/0143-4160(88)90036-X ID - Billger1988 ER - TY - JOUR AU - Di Rosa, G. AU - Odrijin, T. AU - Nixon, R. A. AU - Arancio, O. PY - 2002 DA - 2002// TI - Calpain inhibitors: a treatment for Alzheimer's disease JO - J Mol Neurosci VL - 19 UR - https://doi.org/10.1007/s12031-002-0024-4 DO - 10.1007/s12031-002-0024-4 ID - Di Rosa2002 ER - TY - JOUR AU - Kelly, B. L. AU - Vassar, R. AU - Ferreira, A. PY - 2005 DA - 2005// TI - Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M503259200 DO - 10.1074/jbc.M503259200 ID - Kelly2005 ER - TY - JOUR AU - Nilsson, E. AU - Alafuzoff, I. AU - Blennow, K. AU - Blomgren, K. AU - Hall, C. M. AU - Janson, I. AU - Karlsson, I. AU - Wallin, A. AU - Gottfreis, C. G. AU - Karlsson, J. O. PY - 1990 DA - 1990// TI - Calpain and calpastatin in normal and Alzheimer-degenerated human brain tissue JO - Neurobiol Aging VL - 11 UR - https://doi.org/10.1016/0197-4580(90)90009-O DO - 10.1016/0197-4580(90)90009-O ID - Nilsson1990 ER - TY - JOUR AU - Bird, C. M. AU - Burgess, N. PY - 2008 DA - 2008// TI - The hippocampus and memory: insights from spatial processing JO - Nat Rev Neurosci VL - 9 UR - https://doi.org/10.1038/nrn2335 DO - 10.1038/nrn2335 ID - Bird2008 ER - TY - JOUR AU - Good, M. A. AU - Hale, G. PY - 2007 DA - 2007// TI - The "Swedish" mutation of the amyloid precursor protein (APPswe) dissociates components of object-location memory in aged Tg2576 mice JO - Behav Neurosci VL - 121 UR - https://doi.org/10.1037/0735-7044.121.6.1180 DO - 10.1037/0735-7044.121.6.1180 ID - Good2007 ER - TY - JOUR AU - Squire, L. R. AU - Wixted, J. T. AU - Clark, R. E. PY - 2007 DA - 2007// TI - Recognition memory and the medial temporal lobe: a new perspective JO - Nat Rev Neurosci VL - 8 UR - https://doi.org/10.1038/nrn2154 DO - 10.1038/nrn2154 ID - Squire2007 ER - TY - JOUR AU - Ramos, J. M. AU - Vaquero, J. M. PY - 2005 DA - 2005// TI - The perirhinal cortex of the rat is necessary for spatial memory retention long after but not soon after learning JO - Physiol Behav VL - 86 UR - https://doi.org/10.1016/j.physbeh.2005.07.004 DO - 10.1016/j.physbeh.2005.07.004 ID - Ramos2005 ER - TY - JOUR AU - Barker, G. R. AU - Bird, F. AU - Alexander, V. AU - Warburton, E. C. PY - 2007 DA - 2007// TI - Recognition memory for objects, place, and temporal order: a disconnection analysis of the role of the medial prefrontal cortex and perirhinal cortex JO - J Neurosci VL - 27 UR - https://doi.org/10.1523/JNEUROSCI.5289-06.2007 DO - 10.1523/JNEUROSCI.5289-06.2007 ID - Barker2007 ER - TY - JOUR AU - Rogers, J. L. AU - Kesner, R. P. PY - 2006 DA - 2006// TI - Lesions of the dorsal hippocampus or parietal cortex differentially affect spatial information processing JO - Behav Neurosci VL - 120 UR - https://doi.org/10.1037/0735-7044.120.4.852 DO - 10.1037/0735-7044.120.4.852 ID - Rogers2006 ER - TY - JOUR AU - DeCoteau, W. E. AU - Kesner, R. P. PY - 1998 DA - 1998// TI - Effects of hippocampal and parietal cortex lesions on the processing of multiple-object scenes JO - Behav Neurosci VL - 112 UR - https://doi.org/10.1037/0735-7044.112.1.68 DO - 10.1037/0735-7044.112.1.68 ID - DeCoteau1998 ER - TY - JOUR AU - Heredia, L. AU - Helguera, P. AU - de Olmos, S. AU - Kedikian, G. AU - Solá Vigo, F. AU - LaFerla, F. AU - Staufenbiel, M. AU - de Olmos, J. AU - Busciglio, J. AU - Cáceres, A. AU - Lorenzo, A. PY - 2006 DA - 2006// TI - Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.5567-05.2006 DO - 10.1523/JNEUROSCI.5567-05.2006 ID - Heredia2006 ER - TY - JOUR AU - Song, M. S. AU - Saavedra, L. AU - de Chaves, E. I. PY - 2006 DA - 2006// TI - Apoptosis is secondary to non-apoptotic axonal degeneration in neurons exposed to Aβ in distal axons JO - Neurobiol Aging VL - 27 UR - https://doi.org/10.1016/j.neurobiolaging.2005.06.007 DO - 10.1016/j.neurobiolaging.2005.06.007 ID - Song2006 ER - TY - JOUR AU - Resende, R. AU - Pereira, C. AU - Agostinho, P. AU - Vieira, A. P. AU - Malva, J. O. AU - Oliveira, C. R. PY - 2007 DA - 2007// TI - Susceptibility of hippocampal neurons to Abeta peptide toxicity is associated with perturbation of Ca2+ homeostasis JO - Brain Res VL - 1143 UR - https://doi.org/10.1016/j.brainres.2007.01.071 DO - 10.1016/j.brainres.2007.01.071 ID - Resende2007 ER - TY - JOUR AU - Yao, M. AU - Nguyen, T. V. AU - Pike, C. J. PY - 2005 DA - 2005// TI - Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w JO - J Neurosci VL - 25 UR - https://doi.org/10.1523/JNEUROSCI.4736-04.2005 DO - 10.1523/JNEUROSCI.4736-04.2005 ID - Yao2005 ER - TY - JOUR AU - Fifre, A. AU - Sponne, I. AU - Koziel, V. AU - Kriem, B. AU - Yen Potin, F. T. AU - Bihain, B. E. AU - Olivier, J. L. AU - Oster, T. AU - Pillot, T. PY - 2006 DA - 2006// TI - Microtubule-associated protein MAP1A, MAP1B, and MAP2 proteolysis during soluble amyloid beta-peptide-induced neuronal apoptosis. Synergistic involvement of calpain and caspase-3 JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M507378200 DO - 10.1074/jbc.M507378200 ID - Fifre2006 ER - TY - JOUR AU - Tohda, C. AU - Tamura, T. AU - Komatsu, K. PY - 2003 DA - 2003// TI - Repair of amyloid beta(25–35)-induced memory impairment and synaptic loss by a Kampo formula, Zokumei-to JO - Brain Res VL - 990 UR - https://doi.org/10.1016/S0006-8993(03)03449-8 DO - 10.1016/S0006-8993(03)03449-8 ID - Tohda2003 ER - TY - JOUR AU - Shea, T. B. AU - Cressman, C. M. AU - Spencer, M. J. AU - Beermann, M. L. AU - Nixon, R. A. PY - 1995 DA - 1995// TI - Enhancement of neurite outgrowth following calpain inhibition is mediated by protein kinase C JO - J Neurochem VL - 65 UR - https://doi.org/10.1046/j.1471-4159.1995.65020517.x DO - 10.1046/j.1471-4159.1995.65020517.x ID - Shea1995 ER - TY - JOUR AU - Robles, E. AU - Huttenlocher, A. AU - Gomez, T. M. PY - 2003 DA - 2003// TI - Filopodial calcium transients regulate growth cone motility and guidance through local activation of calpain JO - Neuron VL - 38 UR - https://doi.org/10.1016/S0896-6273(03)00260-5 DO - 10.1016/S0896-6273(03)00260-5 ID - Robles2003 ER - TY - JOUR AU - Nixon, R. A. AU - Saito, K. I. AU - Grynspan, F. AU - Griffin, W. R. AU - Katayama, S. AU - Honda, T. AU - Mohan, P. S. AU - Shea, T. B. AU - Beermann, M. PY - 1994 DA - 1994// TI - Calcium-activated neutral proteinase (calpain) system in aging and Alzheimer's disease JO - Ann NY Acad Sci VL - 747 UR - https://doi.org/10.1111/j.1749-6632.1994.tb44402.x DO - 10.1111/j.1749-6632.1994.tb44402.x ID - Nixon1994 ER - TY - JOUR AU - Doumit, M. E. AU - Koohmaraie, M. PY - 1999 DA - 1999// TI - Immunoblot analysis of calpastatin degradation: evidence for cleavage by calpain in postmortem muscle JO - J Anim Sci VL - 77 ID - Doumit1999 ER - TY - JOUR AU - Vaisid, T. AU - Kosower, N. S. AU - Katzav, A. AU - Chapman, J. AU - Barnoy, S. PY - 2007 DA - 2007// TI - Calpastatin levels affect calpain activation and calpain proteolytic activity in APP transgenic mouse model of Alzheimer's disease JO - Neurochem Int VL - 51 UR - https://doi.org/10.1016/j.neuint.2007.04.004 DO - 10.1016/j.neuint.2007.04.004 ID - Vaisid2007 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1472-6882/8/49/prepub UR - http://www.biomedcentral.com/1472-6882/8/49/prepub ID - ref43 ER -