Healing Potential of Picrorhiza kurroa (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration.

Table 1 The effect of PK and Omez on the levels of TBARS, protein carbonyls, non-protein thiol, and mucin in the ulcerated gastric tissue of mice^a on day one of ulceration

Parameters	Group I mice normal control	Group II 1^st day ulcerated control	Group III PK-treated	Group IV Omez-treated
TBARS (nmoles/mg protein)	0.85 ± 0.03	1.18 ± 0.05^c	0.94 ± 0.06^d	0.89 ± 0.07^d
protein carbonyls (nmoles/mg protein)	1.08 ± 0.05	1.62 ± 0.09^b	1.49 ± 0.12	1.53 ± 0.07
NP-TSH (nmoles/mg tissue)	1.99 ± 0.09	1.66 ± 0.08^b	1.86 ± 0.08	1.81 ± 0.09
mucin (μg/g tissue)	335.03 ± 14.43	213.02 ± 0.59^b	240.33 ± 20.49	253.33 ± 14.53^d

^aStomach ulceration in mice was induced by oral administration of indomethacin (18 mg/kg). PK (20 mg/kg/day × 1 day) and Omez (3 mg/kg/day × 1 day) were used as the test samples. The assays were carried out 4 h after the administration of the test samples. The values are mean ± SEM (n = 15). ^b P < 0.05, ^c P < 0.01 compared to normal mice; ^d P < 0.05 compared to the group II mice.

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