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Table 3 Effect of extract on agar-induced acute edema of the rat paw

From: Acanthus montanus: An experimental evaluation of the antimicrobial, anti-inflammatory and immunological properties of a traditional remedy for furuncles

Extract

Dose (mg/kg)

Edema (ml)

  

0.5 h

1 h

2 h

3 h

4 h

5 h

AE

200

0.14 ± 0.02 (33.33)

0.14 ± 0.02* (44.00)

0.15 ± 0.02* (51.61)

0.14 ± 0.02* (58.82)

0.19 ± 0.07* (57.78)

0.20 ± 0.07* (58.33)

 

400

0.16 ± 0.02 (28.81)

0.16 ± 0.02* (36.0)

0.18 ± 0.03* (41.94)

0.18 ± 0.04* (47.06)

0.26 ± 0.08* (42.22)

0.35 ± 0.05 (27.08)

 

800

0.16 ± 0.02 (28.81)

0.18 ± 0.03* (28.00)

0.23 ± 0.06 (25.81)

0.26 ± 0.07 (23.53)

0.31 ± 0.06 (31.11)

0.36 ± 0.06 (25.0)

Indomethacin

100

0.16 ± 0.01 (28.81)

0.18 ± 0.03* (28.00)

0.18 ± 0.03* (41.94)

0.21 ± 0.03* (38.24)

0.29 ± 0.04 (35.56)

0.30 ± 0.04* (37.50)

Control

-

0.21 ± 0.01

0.25 ± 0.00

0.31 ± 0.01

0.34 ± 0.01

0.45 ± 0.03

0.48 ± 0.01

  1. *Reduction in edema significant at P < 0.05 compared to control (ANOVA; LSD post hoc). Values of edema shown are Mean ± SEM (n = 5); AE = Aqueous extract; Values in parenthesis represent percent inhibition of edema calculated relative to the Control.