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Table 2 Effect of CS on open field exploratory test and behavioural despair test in CMS rats

From: Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress

  Open field exploratory test Behavioural despair test
Groups Total Ambulation Central Ratio Rearing Grooming Immobility period (sec) Immobility period (sec)
Control 75.8 ± 3.6 11.5 ± 0.44 0.1575 22.33 ± 4.10 6.67 ± 1.09 48.16 ± 4.2 72.33 ± 7.1
CMS (0.3% CMC 1 ml/kg) 51.7 ± 2.5** 3.83 ± 0.42* 0.0740 8.83 ± 1.63** 11.5 ± 0.96** 197.83 ± 15.03** 126.33 ± 11.2**
CMS+DZM (2 mg/kg) 68.3 ± 3.78 9.17 ± 0.27 0.1341 14.00 ± 2.1 4.2 ± 0.9†† 36.00 ± 4.69†† 56.17 ± 6.1††
CMS+CS (125 mg/kg) 71.8 ± 6.5 8.33 ± 2.06 0.1160 15.5 ± 1.69 7.5 ± 0.76 79.5 ± 9.9†† 123.3 ± 10.7
CMS+CS (250 mg/kg) 80.0 ± 4.6†† 7.33 ± 2.16 0.0916 23.83 ± 1.30†† 6.33 ± 1.06†† 49.0 ± 5.45†† 120.16 ± 9.7
  1. Data are expressed as mean ± SEM. * and † indicates statistical significance in comparison to control and stress groups respectively and denotes *, † p < 0.05 and **, † † p < 0.01