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Table 2 Effect of CS on open field exploratory test and behavioural despair test in CMS rats

From: Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress

 

Open field exploratory test

Behavioural despair test

Groups

Total

Ambulation Central

Ratio

Rearing

Grooming

Immobility period (sec)

Immobility period (sec)

Control

75.8 ± 3.6

11.5 ± 0.44

0.1575

22.33 ± 4.10

6.67 ± 1.09

48.16 ± 4.2

72.33 ± 7.1

CMS (0.3% CMC 1 ml/kg)

51.7 ± 2.5**

3.83 ± 0.42*

0.0740

8.83 ± 1.63**

11.5 ± 0.96**

197.83 ± 15.03**

126.33 ± 11.2**

CMS+DZM (2 mg/kg)

68.3 ± 3.78†

9.17 ± 0.27†

0.1341

14.00 ± 2.1

4.2 ± 0.9††

36.00 ± 4.69††

56.17 ± 6.1††

CMS+CS (125 mg/kg)

71.8 ± 6.5†

8.33 ± 2.06

0.1160

15.5 ± 1.69

7.5 ± 0.76†

79.5 ± 9.9††

123.3 ± 10.7

CMS+CS (250 mg/kg)

80.0 ± 4.6††

7.33 ± 2.16

0.0916

23.83 ± 1.30††

6.33 ± 1.06††

49.0 ± 5.45††

120.16 ± 9.7

  1. Data are expressed as mean ± SEM. * and † indicates statistical significance in comparison to control and stress groups respectively and denotes *, † p < 0.05 and **, † † p < 0.01