Figure 4

6-shogaol is the most effective individual ginger component in ovarian cancer cells. Transient ginger exposure results in a non-sustained decrease in proliferation of ovarian cancer cells. A: A2780 cells were treated for 24 hours with 75 μg/ml of ginger extract or 7.5 mM of each of the ginger standards. Media containing the indicated compounds was replenished at day 3. Growth was assayed via sulforhodamine B assays on Days 1, 3, 5, and 7. Data are presented as means ± S.D. B. A2780 cells were treated for 24 hours with indicated concentrations of ginger extract or 7.5 mM of 6-gingerol and 6-shogaol. Media containing the indicated compounds was washed off and replaced with complete media after 24 hours. Growth was assayed via sulforhodamine B assays on Days 1, 3, 5, and 7. Data are presented as means ± S.D.