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Table 2 Laboratory-based evaluations of safety

From: Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]

Test

Glucosamine Wk. 0

Glucosamine Wk. 8

Reparagen Wk. 0

Reparagen Wk. 8

Neutrophils %

63.46 ± 1.25

63.54 ± 1.26

62.19 ± 1.32

62.38 ± 1.27

Lymphocytes %

31.73 ± 1.21

32.00 ± 1.27

32.27 ± 1.18

32.27 ± 1.21

Monocytes %

1.17 ± 0.14

1.32 ± 0.15

1.11 ± 0.13

1.16 ± 0.15

Eosinophils %

3.54 ± 0.36

3.22 ± 0.30

4.11 ± 0.47

3.19 ± 0.41

Basophils %

0.02 ± 0.02

0 ± 0

0 ± 0

0 ± 0

White blood cells mm 3

7929 ± 268

7515 ± 222

7753 ± 303

7496 ± 262

Red Blood Cells mm 3

4.06 ± 0.10

4.04 ± 0.08

4.13 ± 0.11

4.15 ± 0.08

Hemoglobin gm/dl

12.02 ± 0.3

12.00 ± 0.2

11.84 ± 0.3

11.92 ± 0.2

Erythrocyte Sedimentation Rate mm

33.0 ± 3.6

30.3 ± 3.0

33.9 ± 3.4

28.5 ± 3.1a

SGPT IU/L

26.3 ± 2.6

23.6 ± 1.7

22.9 ± 2.1

19.9 ± 1.3

Creatinine mg/dl

0.97 ± 0.03

0.93 ± 0.03

1.17 ± 0.21

0.93 ± 0.03

  1. Data expressed as a mean ± SEM.
  2. There was no difference between baseline and week 8 values for the treatment groups with the exception of erythrocyte sedimentation rate as denoted by the letter a (p < 0.05). As the analysis was done on a paired basis completion of the protocol was necessary, hence the analysis is per protocol, glucosamine n = 41, reparagen n = 38.