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Table 1 Effect of Momordica charantia extract on the serum insulin, cholesterol, triglyceride and total protein levels of alloxan diabetic rats

From: An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract

Oral treatment

Insulin μIU/ml (n = 6)

Cholesterol mg% (n = 8)

Triglycerides mg % (n = 8)

Protein g% (n = 8)

 

Mean ± SEM

Normal control

3.5 ± 0.4

78.8 ± 0.8

58.3 ± 0.4

7.7 ± 0.1

Diabetic control

1.6 ± 0.2#

109.6 ± 1.2#

117.1 ± 2.8#

6.0 ± 0.1#

MCE (150 mg/kg)

2.2 ± 0.3

92.2 ± 2.3a

100.3 ± 1.6a

7.1 ± 0.2a

MCE (300 mg/kg)

2.6 ± 0.3c

78.0 ± 1.6a

97.8 ± 2.6a

7.4 ± 0.4a

Glibenclamide (4 mg/kg)

2.7 ± 0.2a

81.5 ± 1.0a

93.2 ± 2.3a

7.5 ± 0.3a

  1. Significant difference of diabetic control from normal control : #P < 0.001
  2. Significant difference of treated groups from diabetic control on the corresponding days: aP < 0.001, cP < 0.01.