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Table 3 Combinatory effect of MAK-4 and MAK-5 on H-ras-induced transformation assessed by focus formation assay

From: MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice

Treatment Exogenous H-ras gene Cytoxicity (% survival) Foci/plate ± SD Relative number of foci
Mock control - 100 0 -
None + 100 81.7 ± 2.3 1.00
MAK-5, 500 μg/ml plus MAK-4, 0 μg/ml + 65 25.3 ± 2.7 0.52
MAK-5, 500 μg/ml plus MAK-4, 100 μg/ml + 81 17.7 ± 0.9 0.28
MAK-5, 500 μg/ml plus MAK-4, 200 μg/ml + 88 20.3 ± 0.8 0.31
  1. The experimental procedure and the duration of treatment was the same as Table 1.