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Table 4 Histological effects of the administration of ethanolic extracts of Baissea axillaries on Rats.

From: Antimicrobial and toxicological evaluation of the leaves of Baissea axillaries Hua used in the management of HIV/AIDS patients

Dosage of administration

Histological effect on Liver tissues

Histological effect on Kidney tissues

Histological effect on Heart tissues

Histological effect on the testes

0.9 ml of normal saline

Tissues appeared normal. No evidence of tissue necrosis

Tissues appeared normal. No evidence of tissue necrosis

Tissues appeared normal. No evidence of tissue necrosis

Tissues appeared normal. No evidence of tissue necrosis

250 mg/kg of Baissea axillaries

Ballooning degeneration of the liver showing signs of early degenerative changes

Tissues appeared normal. No evidence of tissue necrosis

Tissues appeared normal. No evidence of tissue necrosis

Presence of ill defined testes with indistinct cell outlines

500 mg/kg of Baissea axillaries

Densely stained nuclei, increased congestion of the vessels all of which are evidence of tissue necrosis

Tissues appeared normal. No evidence of tissue necrosis

Tissues appeared normal. No evidence of tissue necrosis

Presence of ill defined testes with indistinct cell outlines