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Figure 1 | BMC Complementary and Alternative Medicine

Figure 1

From: The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1β

Figure 1

Enhanced expression of IGF-1 gene in human chondrocytes. IGF-1 gene expression referenced by the activity of β – actin was examined in human chondrocytes (n = 3 for all groups) under basal (control) conditions and after treatment with RNI 249 50 μg/ml (R50), vincaria 10 μg/ml (V10) and their combination (R50 + V10). The * refers to a significant difference from control levels (P < 0.05), and the ** refers to a significant difference from all other groups (P < 0.001), indicating that the combination of R50 and V10 produced significantly greater increases in IGF-1 expression than either V10 or R50 alone.

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