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Table 4 Changes in activities of glutathione peroxidase, glutathione-S-transferase and the levels of reduced glutathione in brain of normal and experimental rats

From: Protective role of Scoparia dulcis plant extract on brain antioxidant status and lipidperoxidation in STZ diabetic male Wistar rats

Groups Glutathione peroxidase (UnitsA/mg protein) Glutathione-S-transferase (UnitsB/mg protein) Reduced glutathione (mg/100g tissue)
Normal 3.4 1± 0.20a 5.62 ± 0.28a 35.19 ± 2.21a
Normal + SPEt (200 mg/kg) 3.80 ± 0.18a 5.90 ± 0.28a 37.12 ± 2.14a
Diabetic control 1.01 ± 0.05b 0.81 ± 0.02b 15.20 ± 1.44b
Diabetic + SPEt (200 mg/kg) 2.62 ± 0.15c 2.10 ± 0.13c 26.02 ± 2.01c
Diabetic + Glibenclamide (600 μg/kg) 1.97 ± 0.12d 2.04 ± 0.13c 25.50 ± 2.10c
  1. Values are given as mean ± SD for 6 rats in each group.
  2. Values not sharing a common superscript letter differ significantly at p < 0.05 (DMRT).
  3. Duncan procedure, Range for the level 2.95, 3.09, 3.20, 3.22.
  4. A – μg of GSH consumed/min.
  5. B – μmoles of CDNB – GSH conjugate formed/min.