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Table 2 Clinical complications and side effects were reported as number per group.

From: Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial [ISRCTN45683816]

Side Effects

Saffron

Imipramine

P

Anxiety

4

1

0.32

Decreased Appetite

2

0

0.48

Increased Appetite

1

5

0.16

Sedation

0

6

0.01

Nausea

2

1

1.00

Headache

3

2

1.00

Dry Mouth

1

7

0.03

Hypomania

2

1

1.00

Constipation

2

5

038

Urinary Retention

1

5

0.16