Table 1 Influence of atropine, mepyramine and propranolol on the hypotensive response of T. arjuna in dogs.
Drug | Dose (n = 6) | Response | |||
|---|---|---|---|---|---|
After Antagonist | |||||
Before Antagonist | Atropine (1 mg) | Mepyramine (20 µg) | Propranolol (30 µg) | ||
T. arjuna | 5 mg/kg | Hypotension | NS | NS | NS |
T. arjuna | 6 mg/kg | Hypotension | No Blockade | No Blockade | Blockade |
T. arjuna | 8 mg/kg | Hypotension | NS | NS | NS |
T. arjuna | 10 mg/kg | Hypotension | NS | NS | NS |
T. arjuna | 15 mg/kg | Hypotension | NS | NS | NS |
T. arjuna | 20 mg/kg(n = 2) | Severe Hypotension | NS | NS | NS |