Table 2 Base-line characteristics of patients evaluated at the end of the run-in period.

47 (12:35)

49 (11:38)

48 (10:38)

49 (10:39)

0.93^c

62.70 (7.22)

62.14 (7.53)

65.10 (3.40)

61.84 (8.95)

0.16^a

60.65 (10.24)

57.65 (10.64)

59.89 (9.74)

59.92 (9.66)

0.49^a

153.94 (6.45)

151.94 (10.71)

152.19 (5.89)

153.32 (6.73)

0.54^a

4.98 (3.32)

3.94 (2.83)

6.09 (4.96)

4.53 (3.86)

0.05^a

0.40^c

2/3

2/6

1/4

3/5

42

41

43

41

22.06 (13.75)

18.94 (14.68)

21.40 (14.97)

19.04 (14.87)

0.63^a

22.04 (4.81)

22.36 (6.00)

24.54 (8.14)

22.77 (5.13)

0.21^a

63.49 (22.36)

64.79 (23.41)

66.87 (22.34)

57.63 (21.21)

0.21^a

10.19 (4.20)

11.02 (4.15)

10.25 (3.86)

10.50 (4.18)

0.75^a

4.51 (1.71)

4.08 (1.95)

4.35 (2.10)

4.27 (1.57)

0.72^a

37.04 (12.00)

35.65 (12.89)

38.00 (13.18)

37.94 (13.02)

0.79^a

51.75 (15.96)

50.76 (17.98)

52.60 (18.13)

52.71 (17.65)

0.94^a

13.78 (3.78)

13.85 (3.22)

14.14 (2.98)

13.73 (2.92)

0.93^a