Figure 6

TRPV4 agonist (GSK1016790A) injection at ST36 yielded no analgesic effect. The behavioral test design was similar to that of MA; one difference was that GSK1016790A was injected at a different concentration and a volume of 10 μL into ST36. (A) Injections of different concentrations of GSK1016790A did not yield significant differences in within-group tests on D3 post and on D4. (B and C) No significant differences were found in between-group tests on D3 post and on D4. Within-group and between-group tests were designed similar to the MA behavioral test (Mann–Whitney rank sum test; n = 8–9). Data are means ± S.E.M.