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Table 1 Expression of BDNF-, pRaf-1-, pMEK1/2-, pERK1/2-, pp90RSK-, and TUNEL-positive cells (counts/1 mm 2 )

From: Electroacupuncture-like stimulation at Baihui and Dazhui acupoints exerts neuroprotective effects through activation of the brain-derived neurotrophic factor-mediated MEK1/2/ERK1/2/p90RSK/bad signaling pathway in mild transient focal cerebral ischemia in rats

 

Sham

Model

EA

Non-acup

U0126 + EA

BDNF

0 ± 0

186 ± 46*

413 ± 60*#

178 ± 51*

393 ± 63*#

pRaf-1

0 ± 0

149 ± 39*

348 ± 55*#

187 ± 67*

338 ± 25*#

pMEK1/2

0 ± 0

165 ± 54*

274 ± 31*#

149 ± 52*

83 ± 54*

pERK1/2

0 ± 0

257 ± 52*

417 ± 36*#

219 ± 57*

198 ± 35*

pp90RSK

0 ± 0

261 ± 107*

497 ± 31*#

302 ± 98*

196 ± 50*

TUNEL

0 ± 0

365 ± 88*

209 ± 59*#

356 ± 80*

339 ± 79*

  1. Mean ± SD (n = 5 or 6). Sham, sham group; Model, model group; EA, EA group; Non-acup, non-acup group; U0126 + EA, U0126 + EA group. *P < 0.05 vs. sham group; #P < 0.05 vs. model group.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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