Table 2 BACE-1 inhibitory in vitro activity of fractions obtained methanol extract of Curcuma longa rhizomes
Material | % inhibition | ||
|---|---|---|---|
2 mg/ml | 1 mg/ml | 0.5 mg/ml | |
Methanol extract | 100 | 65 | 57 |
Hexane-soluble fraction | 85 | 48 | 43 |
Chloroform-soluble fraction | 100 | 81 | 71 |
Ethyl acetate-soluble fraction | 84 | 76 | 70 |
Butanol-soluble fraction | 82 | 26 | 3 |
Water-soluble fraction | 0 | 0 | 0 |